Novel genetic variations associated with salt sensitivity in the Korean population

• Published in: Hypertension research Vol. 34; no. 5; pp. 606 - 611
• Main Authors: Rhee, Moo-Yong, Yang, Soo Jin, Oh, Sang Woo, Park, Yongsoon, Kim, Cho-il, Park, Hye-Kyung, Park, Sung Woo, Park, Cheol-Young
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.05.2011
• Subjects: 631/208/726/649; 692/499; 692/699/75/243; Adult; Asian Continental Ancestry Group - genetics; blood pressure; Blood Pressure - genetics; Female; Fibroblast Growth Factor 5 - genetics; Genetic Association Studies - statistics & numerical data; Genetic Predisposition to Disease; Genetic Variation; Geriatrics/Gerontology; Haplotypes; Health Promotion and Disease Prevention; Humans; Hypertension - epidemiology; Hypertension - genetics; Internal Medicine; Korea - epidemiology; Male; Medicine; Medicine & Public Health; Middle Aged; Obstetrics/Perinatology/Midwifery; original-article; Plasma Membrane Calcium-Transporting ATPases - genetics; Polymorphism, Single Nucleotide; Prevalence; Protein-Serine-Threonine Kinases - genetics; Public Health; salt sensitivity; Salt Tolerance - genetics; single-nucleotide polymorphism; Sodium Chloride, Dietary - administration & dosage; Transaminases - genetics; Korea; single-nucleotide polymorphism; blood pressure; salt sensitivity

Salt sensitivity is a risk factor for cardiovascular morbidity and mortality. To date, only a few genetic variations have been identified as being associated with salt sensitivity. This study aimed to estimate the prevalence of salt sensitivity in the Korean population and to identify genetic varian...