Repetitive Blast Promotes Chronic Aversion to Neutral Cues Encountered in the Peri-Blast Environment

• Published in: Journal of neurotrauma Vol. 38; no. 7; p. 940
• Main Authors: Schindler, Abigail G, Terry, Garth E, Wolden-Hanson, Tami, Cline, Marcella, Park, Michael, Lee, Janet, Yagi, Mayumi, Meabon, James S, Peskind, Elaine R, Raskind, Murray M, Phillips, Paul E M, Cook, David G
• Format: Journal Article
• Language: English
• Published: United States 01.04.2021
• Subjects: Animals; Avoidance Learning - physiology; Blast Injuries - blood; Blast Injuries - complications; Blast Injuries - psychology; Brain Concussion - blood; Brain Concussion - complications; Brain Concussion - psychology; Corticosterone - blood; Cues; Male; Mice; Mice, Inbred C57BL; Odorants; Photic Stimulation - adverse effects; traumatic brain injury; stress; post-traumatic stress disorder; veteran; blast

Repetitive mild traumatic brain injury (mTBI) has been called the "signature injury" of military service members in the Iraq and Afghanistan wars and is highly comorbid with post-traumatic stress disorder (PTSD). Correct attribution of adverse blast-induced mTBI and/or PTSD remains challen...