Stratifin promotes the malignant progression of HCC via binding and hyperactivating AKT signaling - Li, Rong; Yan, Xijing; Zhong, Wenhui; Zheng, Jun; Li, Xuejiao; Liang, Jinliang; Hu, Zhongying; Liu, Huanyi; Chen, Guihua; Yang, Yang; Zhang, Jianwei; Qu, Enze; et al. (Cancer letters, 2024)
Keywords: 14-3-3 Proteins - genetics; 14-3-3 Proteins - metabolism; AKT; Animals; Carcinoma, Hepatocellular - genetics; Carcinoma, Hepatocellular - metabolism; Carcinoma, Hepatocellular - pathology; Cell Line, Tumor; Cell Proliferation; Disease Progression; Exoribonucleases - genetics; Exoribonucleases - metabolism; Female; Gene Expression Regulation, Neoplastic; Hepatocellular carcinoma; Humans; Liver Neoplasms - genetics; Liver Neoplasms - metabolism; Liver Neoplasms - pathology; Male; Malignant progression; Mice; Middle Aged; Prognosis; Proto-Oncogene Proteins c-akt - metabolism; Signal Transduction; Stratifin; Therapeutic target; Hepatocellular carcinoma; AKT; Malignant progression; Stratifin; Therapeutic target