Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice - Gomez, Delphine; Baylis, Richard A; Durgin, Brittany G; Newman, Alexandra A C; Alencar, Gabriel F; Mahan, Sidney; St Hilaire, Cynthia; Müller, Werner; Waisman, Ari; Francis, Sheila E; Pinteaux, Emmanuel; Randolph, Gwendalyn J; et al. (Nature medicine, 2018)
Keywords: Animals; Antibodies; Antibodies, Neutralizing - pharmacology; Apolipoprotein E; Apoptosis - drug effects; Arteriosclerosis; Atherosclerosis; Atherosclerosis - metabolism; Atherosclerosis - pathology; Cell Polarity - drug effects; Cell Proliferation - drug effects; Collagen; Control stability; Down-Regulation - drug effects; Immunoglobulin G; Inflammation; Inflammation - pathology; Interleukin 1; Interleukin 1 receptors; Interleukin-1beta - metabolism; Lesions; Macrophages; Macrophages - drug effects; Macrophages - metabolism; Mice; Mice, Inbred C57BL; Monocytes - drug effects; Monocytes - metabolism; Muscles; Myocardial infarction; Myocytes, Smooth Muscle - drug effects; Myocytes, Smooth Muscle - metabolism; Neutralization Tests; Phenotype; Signal Transduction - drug effects; Smooth muscle; Thromboembolism; Thrombosis