Ovarian Mesonephric-like Adenocarcinoma: Its Prevalence in a Japanese High-Volume Cancer Center and a Literature Review on Therapeutic Targets

• Published in: Current oncology (Toronto) Vol. 31; no. 9; pp. 5107 - 5120
• Main Authors: Ogawa, Ayako, Yoshida, Hiroshi, Kawano, Saria, Kikkawa, Nao, Kobayashi-Kato, Mayumi, Tanase, Yasuhito, Uno, Masaya, Ishikawa, Mitsuya
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 30.08.2024; MDPI
• Subjects: Adenocarcinoma; Adenocarcinoma - pathology; Aged; East Asian People; Female; Health aspects; homologous recombination repair; Humans; immunohistochemistry; Japan - epidemiology; mesonephric-like adenocarcinoma; Metastasis; Middle Aged; Ovarian Neoplasms - genetics; Ovarian Neoplasms - pathology; ovary; Prevalence; Retrospective Studies; therapeutic target; Japan; mesonephric-like adenocarcinoma; ovary; therapeutic target; immunohistochemistry; homologous recombination repair

Ovarian mesonephric-like adenocarcinoma (MLA) is a newly described histological type known for its aggressive behavior. This study aims to determine the frequency of ovarian MLA, review the existing literature, and elucidate its clinicopathological characteristics, including the potential therapeuti...