Development and Validation of MRI-Based Radiomics Models for Diagnosing Juvenile Myoclonic Epilepsy
Radiomic modeling using multiple regions of interest in MRI of the brain to diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This study aimed to develop and validate radiomics prediction models to distinguish patients with JME from healthy controls (HCs), and to evaluate the...
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Published in | Korean journal of radiology Vol. 23; no. 12; pp. 1281 - 1289 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Korea (South)
The Korean Society of Radiology
01.12.2022
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Abstract | Radiomic modeling using multiple regions of interest in MRI of the brain to diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This study aimed to develop and validate radiomics prediction models to distinguish patients with JME from healthy controls (HCs), and to evaluate the feasibility of a radiomics approach using MRI for diagnosing JME.
A total of 97 JME patients (25.6 ± 8.5 years; female, 45.5%) and 32 HCs (28.9 ± 11.4 years; female, 50.0%) were randomly split (7:3 ratio) into a training (n = 90) and a test set (n = 39) group. Radiomic features were extracted from 22 regions of interest in the brain using the T1-weighted MRI based on clinical evidence. Predictive models were trained using seven modeling methods, including a light gradient boosting machine, support vector classifier, random forest, logistic regression, extreme gradient boosting, gradient boosting machine, and decision tree, with radiomics features in the training set. The performance of the models was validated and compared to the test set. The model with the highest area under the receiver operating curve (AUROC) was chosen, and important features in the model were identified.
The seven tested radiomics models, including light gradient boosting machine, support vector classifier, random forest, logistic regression, extreme gradient boosting, gradient boosting machine, and decision tree, showed AUROC values of 0.817, 0.807, 0.783, 0.779, 0.767, 0.762, and 0.672, respectively. The light gradient boosting machine with the highest AUROC, albeit without statistically significant differences from the other models in pairwise comparisons, had accuracy, precision, recall, and F1 scores of 0.795, 0.818, 0.931, and 0.871, respectively. Radiomic features, including the putamen and ventral diencephalon, were ranked as the most important for suggesting JME.
Radiomic models using MRI were able to differentiate JME from HCs. |
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AbstractList | Objective Radiomic modeling using multiple regions of interest in MRI of the brain to diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This study aimed to develop and validate radiomics prediction models to distinguish patients with JME from healthy controls (HCs), and to evaluate the feasibility of a radiomics approach using MRI for diagnosing JME. Materials and Methods A total of 97 JME patients (25.6 ± 8.5 years; female, 45.5%) and 32 HCs (28.9 ± 11.4 years; female, 50.0%) were randomly split (7:3 ratio) into a training (n = 90) and a test set (n = 39) group. Radiomic features were extracted from 22 regions of interest in the brain using the T1-weighted MRI based on clinical evidence. Predictive models were trained using seven modeling methods, including a light gradient boosting machine, support vector classifier, random forest, logistic regression, extreme gradient boosting, gradient boosting machine, and decision tree, with radiomics features in the training set. The performance of the models was validated and compared to the test set. The model with the highest area under the receiver operating curve (AUROC) was chosen, and important features in the model were identified. Results The seven tested radiomics models, including light gradient boosting machine, support vector classifier, random forest, logistic regression, extreme gradient boosting, gradient boosting machine, and decision tree, showed AUROC values of 0.817, 0.807, 0.783, 0.779, 0.767, 0.762, and 0.672, respectively. The light gradient boosting machine with the highest AUROC, albeit without statistically significant differences from the other models in pairwise comparisons, had accuracy, precision, recall, and F1 scores of 0.795, 0.818, 0.931, and 0.871, respectively. Radiomic features, including the putamen and ventral diencephalon, were ranked as the most important for suggesting JME. Conclusion Radiomic models using MRI were able to differentiate JME from HCs. Radiomic modeling using multiple regions of interest in MRI of the brain to diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This study aimed to develop and validate radiomics prediction models to distinguish patients with JME from healthy controls (HCs), and to evaluate the feasibility of a radiomics approach using MRI for diagnosing JME. A total of 97 JME patients (25.6 ± 8.5 years; female, 45.5%) and 32 HCs (28.9 ± 11.4 years; female, 50.0%) were randomly split (7:3 ratio) into a training (n = 90) and a test set (n = 39) group. Radiomic features were extracted from 22 regions of interest in the brain using the T1-weighted MRI based on clinical evidence. Predictive models were trained using seven modeling methods, including a light gradient boosting machine, support vector classifier, random forest, logistic regression, extreme gradient boosting, gradient boosting machine, and decision tree, with radiomics features in the training set. The performance of the models was validated and compared to the test set. The model with the highest area under the receiver operating curve (AUROC) was chosen, and important features in the model were identified. The seven tested radiomics models, including light gradient boosting machine, support vector classifier, random forest, logistic regression, extreme gradient boosting, gradient boosting machine, and decision tree, showed AUROC values of 0.817, 0.807, 0.783, 0.779, 0.767, 0.762, and 0.672, respectively. The light gradient boosting machine with the highest AUROC, albeit without statistically significant differences from the other models in pairwise comparisons, had accuracy, precision, recall, and F1 scores of 0.795, 0.818, 0.931, and 0.871, respectively. Radiomic features, including the putamen and ventral diencephalon, were ranked as the most important for suggesting JME. Radiomic models using MRI were able to differentiate JME from HCs. |
Author | Han, Kyunghwa Kim, Kyung Min Ahn, Sung Soo Chu, Min Kyung Heo, Kyoung Lee, Seung-Koo Park, Kisung Sohn, Beomseok Hwang, Heewon Lee, Wonwoo |
AuthorAffiliation | 2 Department of Neurology, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea 1 Department of Neurology, Epilepsy Research Institute, Yonsei University College of Medicine, Seoul, Korea 3 Department of Radiology, Severance Hospital, Research Institute of Radiological Science and Centre for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, Korea 5 Department of Neurology, Yongin Severance Hospital, Yonsei University Health System, Yongin, Korea 4 Department of Mechanical Engineering, Pohang University of Science and Technology, Pohang, Korea |
AuthorAffiliation_xml | – name: 3 Department of Radiology, Severance Hospital, Research Institute of Radiological Science and Centre for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, Korea – name: 5 Department of Neurology, Yongin Severance Hospital, Yonsei University Health System, Yongin, Korea – name: 4 Department of Mechanical Engineering, Pohang University of Science and Technology, Pohang, Korea – name: 1 Department of Neurology, Epilepsy Research Institute, Yonsei University College of Medicine, Seoul, Korea – name: 2 Department of Neurology, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea |
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Cites_doi | 10.1136/bmj.g7594 10.1093/brain/aws296 10.1016/j.pnpbp.2010.02.009 10.1016/j.yebeh.2012.06.024 10.1111/epi.12634 10.1016/j.neuroimage.2006.04.174 10.1613/jair.953 10.1111/epi.12330 10.1093/sleep/14.6.540 10.1016/j.eplepsyres.2013.07.003 10.1016/j.nicl.2018.11.014 10.1016/j.yebeh.2016.07.015 10.1016/j.seizure.2015.06.009 10.1158/0008-5472.CAN-17-0339 10.1006/nimg.1998.0395 10.1111/j.1528-1167.2011.03313.x 10.1111/j.1528-1157.1989.tb05316.x 10.1148/radiol.2015151169 10.1016/j.yebeh.2011.05.018 10.3390/brainsci12050553 10.1111/j.1528-1167.2012.03544.x 10.1111/j.1528-1167.2012.03526.x 10.3389/fncel.2019.00433 10.1111/j.1528-1167.2011.03117.x 10.1111/j.1528-1167.2010.02569.x 10.1016/j.neuroimage.2004.03.032 10.1111/j.1528-1167.2009.02127.x 10.1016/j.yebeh.2012.12.009 10.1155/2018/7392187 10.1016/S0896-6273(02)00569-X 10.3348/kjr.2006.7.3.162 10.1212/WNL.0b013e318203e93d 10.1016/j.seizure.2013.01.001 10.1109/TMI.2006.887364 10.1002/hbm.22405 10.1038/nrclinonc.2017.141 10.1111/epi.16392 10.1016/j.nicl.2018.04.024 10.1016/j.eplepsyres.2021.106569 10.1002/brb3.2274 10.1038/ncomms5006 10.1212/WNL.0000000000008173 10.1212/01.wnl.0000316120.70504.d5 10.3389/fneur.2022.883078 10.1016/j.yebeh.2013.06.034 10.1111/ane.13198 10.1136/pmj.79.928.78 10.1007/s00415-013-6891-5 10.1016/j.eplepsyres.2017.04.002 10.1093/brain/122.11.2101 |
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Keywords | Idiopathic generalized epilepsy Texture analysis Magnetic resonance imaging Juvenile myoclonic epilepsy Radiomics |
Language | English |
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References | 36725358 - Korean J Radiol. 2023 Feb;24(2):166-167 36725357 - Korean J Radiol. 2023 Feb;24(2):168-169 Kim (10.3348/kjr.2022.0539_ref30) 2013; 260 Fischl (10.3348/kjr.2022.0539_ref16) 2002; 33 Lambin (10.3348/kjr.2022.0539_ref37) 2017; 14 Liu (10.3348/kjr.2022.0539_ref43) 2011; 52 Ur Özçelik (10.3348/kjr.2022.0539_ref31) 2021; 171 Aerts (10.3348/kjr.2022.0539_ref11) 2014; 5 Gilsoul (10.3348/kjr.2022.0539_ref34) 2019; 13 Wang (10.3348/kjr.2022.0539_ref10) 2019; 21 10.3348/kjr.2022.0539_ref40 Landvogt (10.3348/kjr.2022.0539_ref50) 2010; 51 Keller (10.3348/kjr.2022.0539_ref7) 2011; 52 O’Muircheartaigh (10.3348/kjr.2022.0539_ref4) 2012; 135 Betting (10.3348/kjr.2022.0539_ref42) 2006; 32 Camfield (10.3348/kjr.2022.0539_ref1) 2013; 28 Suppl 1 Ciumas (10.3348/kjr.2022.0539_ref24) 2008; 71 Gillies (10.3348/kjr.2022.0539_ref12) 2016; 278 Kim (10.3348/kjr.2022.0539_ref47) 2012; 53 Si (10.3348/kjr.2022.0539_ref48) 2020; 2020 Alhusaini (10.3348/kjr.2022.0539_ref45) 2013; 54 Mo (10.3348/kjr.2022.0539_ref13) 2019; 60 Cao (10.3348/kjr.2022.0539_ref3) 2013; 106 Tae (10.3348/kjr.2022.0539_ref26) 2006; 7 Zhang (10.3348/kjr.2022.0539_ref28) 2022; 13 Focke (10.3348/kjr.2022.0539_ref19) 2014; 35 Geithner (10.3348/kjr.2022.0539_ref41) 2012; 53 Johns (10.3348/kjr.2022.0539_ref49) 1991; 14 Filho (10.3348/kjr.2022.0539_ref8) 2010; 34 Roebling (10.3348/kjr.2022.0539_ref5) 2009; 50 Zhong (10.3348/kjr.2022.0539_ref22) 2018; 2018 Collins (10.3348/kjr.2022.0539_ref38) 2015; 350 (10.3348/kjr.2022.0539_ref2) 1989; 30 Bartolini (10.3348/kjr.2022.0539_ref23) 2014; 55 O’Muircheartaigh (10.3348/kjr.2022.0539_ref32) 2011; 76 van Griethuysen (10.3348/kjr.2022.0539_ref36) 2017; 77 de Oliveira (10.3348/kjr.2022.0539_ref6) 2013; 27 Woermann (10.3348/kjr.2022.0539_ref44) 1999; 122 Kim (10.3348/kjr.2022.0539_ref33) 2015; 30 Lin (10.3348/kjr.2022.0539_ref27) 2013; 29 Mory (10.3348/kjr.2022.0539_ref29) 2011; 21 Chawla (10.3348/kjr.2022.0539_ref39) 2002; 16 Lee (10.3348/kjr.2022.0539_ref51) 2020; 141 Saini (10.3348/kjr.2022.0539_ref21) 2013; 22 Dale (10.3348/kjr.2022.0539_ref18) 1999; 9 Ekmekci (10.3348/kjr.2022.0539_ref20) 2016; 62 Lee (10.3348/kjr.2022.0539_ref9) 2021; 11 Rossi (10.3348/kjr.2022.0539_ref25) 2022; 12 Ségonne (10.3348/kjr.2022.0539_ref15) 2004; 22 Renganathan (10.3348/kjr.2022.0539_ref52) 2003; 79 Liu (10.3348/kjr.2022.0539_ref14) 2018; 19 Ségonne (10.3348/kjr.2022.0539_ref17) 2007; 26 Wandschneider (10.3348/kjr.2022.0539_ref46) 2019; 93 Gong (10.3348/kjr.2022.0539_ref35) 2017; 135 |
References_xml | – volume: 350 start-page: g7594 year: 2015 ident: 10.3348/kjr.2022.0539_ref38 publication-title: BMJ doi: 10.1136/bmj.g7594 contributor: fullname: Collins – volume: 135 start-page: 3635 issue: Pt 12 year: 2012 ident: 10.3348/kjr.2022.0539_ref4 publication-title: Brain doi: 10.1093/brain/aws296 contributor: fullname: O’Muircheartaigh – volume: 34 start-page: 516 year: 2010 ident: 10.3348/kjr.2022.0539_ref8 publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/j.pnpbp.2010.02.009 contributor: fullname: Filho – volume: 28 Suppl 1 start-page: S15 year: 2013 ident: 10.3348/kjr.2022.0539_ref1 publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2012.06.024 contributor: fullname: Camfield – volume: 55 start-page: 1038 year: 2014 ident: 10.3348/kjr.2022.0539_ref23 publication-title: Epilepsia doi: 10.1111/epi.12634 contributor: fullname: Bartolini – volume: 32 start-page: 498 year: 2006 ident: 10.3348/kjr.2022.0539_ref42 publication-title: Neuroimage doi: 10.1016/j.neuroimage.2006.04.174 contributor: fullname: Betting – volume: 16 start-page: 321 year: 2002 ident: 10.3348/kjr.2022.0539_ref39 publication-title: J Artif Intell Res doi: 10.1613/jair.953 contributor: fullname: Chawla – volume: 54 start-page: e138 year: 2013 ident: 10.3348/kjr.2022.0539_ref45 publication-title: Epilepsia doi: 10.1111/epi.12330 contributor: fullname: Alhusaini – volume: 14 start-page: 540 year: 1991 ident: 10.3348/kjr.2022.0539_ref49 publication-title: Sleep doi: 10.1093/sleep/14.6.540 contributor: fullname: Johns – volume: 106 start-page: 370 year: 2013 ident: 10.3348/kjr.2022.0539_ref3 publication-title: Epilepsy Res doi: 10.1016/j.eplepsyres.2013.07.003 contributor: fullname: Cao – volume: 21 start-page: 101604 year: 2019 ident: 10.3348/kjr.2022.0539_ref10 publication-title: Neuroimage Clin doi: 10.1016/j.nicl.2018.11.014 contributor: fullname: Wang – volume: 62 start-page: 166 year: 2016 ident: 10.3348/kjr.2022.0539_ref20 publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2016.07.015 contributor: fullname: Ekmekci – volume: 30 start-page: 124 year: 2015 ident: 10.3348/kjr.2022.0539_ref33 publication-title: Seizure doi: 10.1016/j.seizure.2015.06.009 contributor: fullname: Kim – volume: 77 start-page: e104 year: 2017 ident: 10.3348/kjr.2022.0539_ref36 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-17-0339 contributor: fullname: van Griethuysen – volume: 9 start-page: 179 year: 1999 ident: 10.3348/kjr.2022.0539_ref18 publication-title: Neuroimage doi: 10.1006/nimg.1998.0395 contributor: fullname: Dale – volume: 52 start-page: 2267 year: 2011 ident: 10.3348/kjr.2022.0539_ref43 publication-title: Epilepsia doi: 10.1111/j.1528-1167.2011.03313.x contributor: fullname: Liu – volume: 30 start-page: 389 year: 1989 ident: 10.3348/kjr.2022.0539_ref2 publication-title: Epilepsia doi: 10.1111/j.1528-1157.1989.tb05316.x – volume: 278 start-page: 563 year: 2016 ident: 10.3348/kjr.2022.0539_ref12 publication-title: Radiology doi: 10.1148/radiol.2015151169 contributor: fullname: Gillies – volume: 21 start-page: 407 year: 2011 ident: 10.3348/kjr.2022.0539_ref29 publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2011.05.018 contributor: fullname: Mory – volume: 12 start-page: 553 year: 2022 ident: 10.3348/kjr.2022.0539_ref25 publication-title: Brain Sci doi: 10.3390/brainsci12050553 contributor: fullname: Rossi – volume: 53 start-page: 1371 year: 2012 ident: 10.3348/kjr.2022.0539_ref47 publication-title: Epilepsia doi: 10.1111/j.1528-1167.2012.03544.x contributor: fullname: Kim – volume: 53 start-page: 1379 year: 2012 ident: 10.3348/kjr.2022.0539_ref41 publication-title: Epilepsia doi: 10.1111/j.1528-1167.2012.03526.x contributor: fullname: Geithner – volume: 13 start-page: 433 year: 2019 ident: 10.3348/kjr.2022.0539_ref34 publication-title: Front Cell Neurosci doi: 10.3389/fncel.2019.00433 contributor: fullname: Gilsoul – volume: 52 start-page: 1715 year: 2011 ident: 10.3348/kjr.2022.0539_ref7 publication-title: Epilepsia doi: 10.1111/j.1528-1167.2011.03117.x contributor: fullname: Keller – volume: 51 start-page: 1699 year: 2010 ident: 10.3348/kjr.2022.0539_ref50 publication-title: Epilepsia doi: 10.1111/j.1528-1167.2010.02569.x contributor: fullname: Landvogt – volume: 22 start-page: 1060 year: 2004 ident: 10.3348/kjr.2022.0539_ref15 publication-title: Neuroimage doi: 10.1016/j.neuroimage.2004.03.032 contributor: fullname: Ségonne – volume: 50 start-page: 2456 year: 2009 ident: 10.3348/kjr.2022.0539_ref5 publication-title: Epilepsia doi: 10.1111/j.1528-1167.2009.02127.x contributor: fullname: Roebling – volume: 27 start-page: 22 year: 2013 ident: 10.3348/kjr.2022.0539_ref6 publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2012.12.009 contributor: fullname: de Oliveira – volume: 2018 start-page: 7392187 year: 2018 ident: 10.3348/kjr.2022.0539_ref22 publication-title: Neural Plast doi: 10.1155/2018/7392187 contributor: fullname: Zhong – volume: 33 start-page: 341 year: 2002 ident: 10.3348/kjr.2022.0539_ref16 publication-title: Neuron doi: 10.1016/S0896-6273(02)00569-X contributor: fullname: Fischl – volume: 7 start-page: 162 year: 2006 ident: 10.3348/kjr.2022.0539_ref26 publication-title: Korean J Radiol doi: 10.3348/kjr.2006.7.3.162 contributor: fullname: Tae – volume: 76 start-page: 34 year: 2011 ident: 10.3348/kjr.2022.0539_ref32 publication-title: Neurology doi: 10.1212/WNL.0b013e318203e93d contributor: fullname: O’Muircheartaigh – volume: 22 start-page: 230 year: 2013 ident: 10.3348/kjr.2022.0539_ref21 publication-title: Seizure doi: 10.1016/j.seizure.2013.01.001 contributor: fullname: Saini – volume: 26 start-page: 518 year: 2007 ident: 10.3348/kjr.2022.0539_ref17 publication-title: IEEE Trans Med Imaging doi: 10.1109/TMI.2006.887364 contributor: fullname: Ségonne – volume: 35 start-page: 3332 year: 2014 ident: 10.3348/kjr.2022.0539_ref19 publication-title: Hum Brain Mapp doi: 10.1002/hbm.22405 contributor: fullname: Focke – volume: 14 start-page: 749 year: 2017 ident: 10.3348/kjr.2022.0539_ref37 publication-title: Nat Rev Clin Oncol doi: 10.1038/nrclinonc.2017.141 contributor: fullname: Lambin – volume: 60 start-page: 2519 year: 2019 ident: 10.3348/kjr.2022.0539_ref13 publication-title: Epilepsia doi: 10.1111/epi.16392 contributor: fullname: Mo – volume: 19 start-page: 271 year: 2018 ident: 10.3348/kjr.2022.0539_ref14 publication-title: Neuroimage Clin doi: 10.1016/j.nicl.2018.04.024 contributor: fullname: Liu – volume: 171 start-page: 106569 year: 2021 ident: 10.3348/kjr.2022.0539_ref31 publication-title: Epilepsy Res doi: 10.1016/j.eplepsyres.2021.106569 contributor: fullname: Ur Özçelik – volume: 11 start-page: e2274 year: 2021 ident: 10.3348/kjr.2022.0539_ref9 publication-title: Brain Behav doi: 10.1002/brb3.2274 contributor: fullname: Lee – volume: 5 start-page: 4006 year: 2014 ident: 10.3348/kjr.2022.0539_ref11 publication-title: Nat Commun doi: 10.1038/ncomms5006 contributor: fullname: Aerts – volume: 93 start-page: e1272 year: 2019 ident: 10.3348/kjr.2022.0539_ref46 publication-title: Neurology doi: 10.1212/WNL.0000000000008173 contributor: fullname: Wandschneider – ident: 10.3348/kjr.2022.0539_ref40 – volume: 71 start-page: 788 year: 2008 ident: 10.3348/kjr.2022.0539_ref24 publication-title: Neurology doi: 10.1212/01.wnl.0000316120.70504.d5 contributor: fullname: Ciumas – volume: 13 start-page: 883078 year: 2022 ident: 10.3348/kjr.2022.0539_ref28 publication-title: Front Neurol doi: 10.3389/fneur.2022.883078 contributor: fullname: Zhang – volume: 2020 start-page: 1679 year: 2020 ident: 10.3348/kjr.2022.0539_ref48 publication-title: Annu Int Conf IEEE Eng Med Biol Soc contributor: fullname: Si – volume: 29 start-page: 247 year: 2013 ident: 10.3348/kjr.2022.0539_ref27 publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2013.06.034 contributor: fullname: Lin – volume: 141 start-page: 271 year: 2020 ident: 10.3348/kjr.2022.0539_ref51 publication-title: Acta Neurol Scand doi: 10.1111/ane.13198 contributor: fullname: Lee – volume: 79 start-page: 78 year: 2003 ident: 10.3348/kjr.2022.0539_ref52 publication-title: Postgrad Med J doi: 10.1136/pmj.79.928.78 contributor: fullname: Renganathan – volume: 260 start-page: 1846 year: 2013 ident: 10.3348/kjr.2022.0539_ref30 publication-title: J Neurol doi: 10.1007/s00415-013-6891-5 contributor: fullname: Kim – volume: 135 start-page: 1 year: 2017 ident: 10.3348/kjr.2022.0539_ref35 publication-title: Epilepsy Res doi: 10.1016/j.eplepsyres.2017.04.002 contributor: fullname: Gong – volume: 122 start-page: 2101 issue: Pt 11 year: 1999 ident: 10.3348/kjr.2022.0539_ref44 publication-title: Brain doi: 10.1093/brain/122.11.2101 contributor: fullname: Woermann |
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Snippet | Radiomic modeling using multiple regions of interest in MRI of the brain to diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This... Objective Radiomic modeling using multiple regions of interest in MRI of the brain to diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated.... |
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SubjectTerms | Adult Age Area Under Curve Automation Brain - diagnostic imaging Brain research Convulsions & seizures Electroencephalography Epilepsy Female Humans Machine learning Magnetic Resonance Imaging Male Morphology Myoclonic Epilepsy, Juvenile - diagnostic imaging Neuroimaging and Head & Neck Patients Regression analysis Software |
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Title | Development and Validation of MRI-Based Radiomics Models for Diagnosing Juvenile Myoclonic Epilepsy |
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