CEBPB regulates the migration, invasion and EMT of breast cancer cells by inhibiting THBS2 expression and O-fucosylation

• Published in: Human Molecular Genetics Vol. 32; no. 11; pp. 1850 - 1863
• Main Authors: Qi, Liqiang, Sun, Bo, Yang, Beibei, Lu, Su
• Format: Journal Article
• Language: English
• Published: England Oxford University Press (OUP) 18.05.2023; Oxford University Press
• Subjects: Breast Neoplasms; Breast Neoplasms - metabolism; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-beta - genetics; Cell Line; Cell Line, Tumor; Cell Movement; Cell Movement - genetics; Cell Proliferation; Cell Proliferation - genetics; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; MicroRNAs - genetics; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 3-Kinases - genetics; Signal Transduction; Signal Transduction - genetics

Abstract Breast cancer (bc) is the second most common type of human malignancies with highest morbidity and mortality in the female population. Therefore, it is essential to develop novel and effective therapies for bc treatment. The main aim of the current study is to investigate the functions of C...