Chloride is required for fluid transport by the rabbit corneal endothelium

• Published in: The American journal of physiology Vol. 262; no. 5 Pt 1; p. C1167
• Main Authors: Winkler, B S, Riley, M V, Peters, M I, Williams, F J
• Format: Journal Article
• Language: English
• Published: United States 01.05.1992
• Subjects: Animals; Body Fluids - metabolism; Body Water - metabolism; Chlorides - pharmacology; Chlorides - physiology; Cornea - metabolism; Culture Media; Endothelium, Corneal - drug effects; Endothelium, Corneal - metabolism; Gluconates - pharmacology; In Vitro Techniques; Rabbits; Stilbenes - pharmacology

The role of chloride in fluid transport of the rabbit corneal endothelium was examined by measuring changes in corneal thickness following ion substitutions or addition of ion transport inhibitors in media superfusing the isolated tissue. Normal fluid transport is indicated by maintenance of constan...