Extended application of the rapid post-mortem test kit for bovine spongiform encephalopathy to chronic wasting disease

Chronic wasting disease (CWD) is a prion disease affecting cervid species primarily in the United States of America and Canada; however, it is now emerging in Scandinavian countries. Although CWD cases have not been reported in Japan, in case of a CWD outbreak occuring, it is critical to prepare for...

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Published inMicrobiology and immunology Vol. 66; no. 5; p. 212
Main Authors Matsuura, Yuichi, Miyazawa, Kohtaro, Horiuchi, Motohiro, Suzuki, Akio, Yokoyama, Mayumi, Imamura, Morikazu, Ikeda, Keigo, Iwamaru, Yoshifumi
Format Journal Article
LanguageEnglish
Published Australia 01.05.2022
Subjects
Animals
Cattle
Deer
Encephalopathy, Bovine Spongiform - diagnosis
Japan
Prions
Wasting Disease, Chronic - diagnosis
Wasting Disease, Chronic - epidemiology
Japan
rapid post-mortem test kit
PRNP
prion
Chronic wasting disease (CWD)
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Summary:Chronic wasting disease (CWD) is a prion disease affecting cervid species primarily in the United States of America and Canada; however, it is now emerging in Scandinavian countries. Although CWD cases have not been reported in Japan, in case of a CWD outbreak occuring, it is critical to prepare for testing a large number of specimens. The present study showed that a rapid post-mortem test kit, which is used for bovine spongiform encephalopathy surveillance in Japan, is valid for the detection of CWD prion.
ISSN:1348-0421
DOI:10.1111/1348-0421.12968