Immunosuppression in pediatric liver transplant recipients: Unique aspects

• Published in: Liver transplantation Vol. 23; no. 2; pp. 244 - 256
• Main Authors: Miloh, Tamir, Barton, Andrea, Wheeler, Justin, Pham, Yen, Hewitt, Winston, Keegan, Tara, Sanchez, Christine, Bulut, Pinar, Goss, John
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.02.2017
• Subjects: Adolescent; Adult; Age Factors; Child; Communicable Diseases - epidemiology; Communicable Diseases - etiology; Communicable Diseases - immunology; Counseling; End Stage Liver Disease - mortality; End Stage Liver Disease - surgery; Graft Rejection - immunology; Graft Rejection - prevention & control; Graft Survival - immunology; Humans; Immune Tolerance; Immunosuppression - adverse effects; Immunosuppression - methods; Immunosuppressive Agents - pharmacology; Immunosuppressive Agents - therapeutic use; Liver; Liver - immunology; Liver Transplantation - adverse effects; Patient Compliance - psychology; Patient Transfer; Pediatrics; Transplant Recipients - psychology; Transplants & implants; Treatment Outcome

Pediatric liver transplantation has experienced improved outcomes over the last 50 years. This can be attributed in part to establishing optimal use of immunosuppressive agents to achieve a balance between minimizing the risks of allograft rejection and infection. The management of immunosuppression...