A confirmatory study on the efficacy of dehydrated human amnion/chorion membrane dHACM allograft in the management of diabetic foot ulcers: A prospective, multicentre, randomised, controlled study of 110 patients from 14 wound clinics

• Published in: International wound journal Vol. 16; no. 1; pp. 19 - 29
• Main Authors: Tettelbach, William, Cazzell, Shawn, Reyzelman, Alexander M, Sigal, Felix, Caporusso, Joseph M, Agnew, Patrick S
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.02.2019
• Subjects: Adult; advanced wound care; Aged; Aged, 80 and over; Allografts - transplantation; Amnion - transplantation; amniotic membrane; Chorion - transplantation; dehydrated human amnion/chorion membrane; Diabetic Foot - surgery; diabetic ulcers; Female; Humans; lower extremity ulcers; Male; Middle Aged; Original; Prospective Studies; Skin, Artificial; Transplantation, Homologous - methods; Treatment Outcome; United States; Wound Healing - physiology; United States; diabetic ulcers; dehydrated human amnion/chorion membrane; lower extremity ulcers; amniotic membrane; advanced wound care

A randomised, controlled multicentre clinical trial was conducted at 14 wound care centres in the United States to confirm the efficacy of dehydrated human amnion/chorion membrane allograft (dHACM) for the treatment of chronic lower extremity ulcers in persons with diabetes. Patients with a lower ex...