Effects of β‐Adrenergic Blockade on Left Ventricular Remodeling Among Hispanics and African Americans With Chronic Heart Failure

• Published in: Clinical cardiology (Mahwah, N.J.) Vol. 36; no. 10; pp. 595 - 602
• Main Authors: Kelesidis, Iosif, Varughese, Christopher J., Hourani, Patrick, Zolty, Ronald
• Format: Journal Article
• Language: English
• Published: New York Wiley Periodicals, Inc 01.10.2013
• Subjects: Adrenergic beta-Antagonists - therapeutic use; African Americans; Aged; Chronic Disease; Clinical Investigation; Clinical Investigations; European Continental Ancestry Group; Female; Heart Failure - diagnosis; Heart Failure - drug therapy; Heart Failure - ethnology; Heart Failure - physiopathology; Hispanic Americans; Humans; Linear Models; Logistic Models; Male; Middle Aged; Mitral Valve Insufficiency - drug therapy; Mitral Valve Insufficiency - ethnology; Mitral Valve Insufficiency - physiopathology; Multivariate Analysis; Odds Ratio; Retrospective Studies; Risk Factors; Stroke Volume - drug effects; Time Factors; Treatment Outcome; United States - epidemiology; Ventricular Function, Left - drug effects; Ventricular Remodeling - drug effects; United States

Background Although β‐blockers (BBs) have been shown to improve cardiac function, there is individual and ethnic variation in BB clinical response. We examined the effects of BBs on left ventricular remodeling among African Americans (AAs), Hispanics, and Caucasians with systolic heart failure. Hypo...