Intermediate filament protein evolution and protists

• Published in: Cytoskeleton (Hoboken, N.J.) Vol. 75; no. 6; pp. 231 - 243
• Main Authors: Preisner, Harald, Habicht, Jörn, Garg, Sriram G., Gould, Sven B.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.06.2018
• Subjects: Actin; Animals; Biological Evolution; Cytoskeleton; eukaryote evolution; Eukaryotes; Eukaryotic Cells - cytology; Evolution; Filaments; Genomes; Intermediate Filaments; Keratin; Lamins; multicellularity; Phylogenetics; Phylogeny; Prokaryotic Cells - cytology; Proteins; Structure-function relationships; Tubulin; Vimentin; multicellularity; lamins; cytoskeleton; eukaryote evolution; intermediate filaments

Metazoans evolved from a single protist lineage. While all eukaryotes share a conserved actin and tubulin‐based cytoskeleton, it is commonly perceived that intermediate filaments (IFs), including lamin, vimentin or keratin among many others, are restricted to metazoans. Actin and tubulin proteins ar...