Radiotherapy, photodynamic therapy, and cryoablation‐induced abscopal effect: Challenges and future prospects

• Published in: Cancer innovation (Print) Vol. 2; no. 5; pp. 323 - 345
• Main Authors: Ali Mohammad, Sadik, Hak, Arshadul, Pogu, Sunil V., Rengan, Aravind K.
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.10.2023; John Wiley and Sons Inc; Wiley
• Subjects: abscopal effect; Adenosine triphosphate; Antigens; Apoptosis; cancer; Cancer therapies; Case reports; Cell death; Chemotherapy; Combination therapy; cryoablation; Cytotoxicity; Endoplasmic reticulum; Immunotherapy; Ligands; local therapy; Lymphocytes; Lymphoma; Metastasis; Photodynamic therapy; Radiation therapy; radiotherapy; Review; Tumor necrosis factor-TNF; Tumors; local therapy; cryoablation; photodynamic therapy; immunotherapy; radiotherapy; cancer; abscopal effect

Local therapy modalities such as radiation therapy, photodynamic therapy, photothermal therapy, and cryoablation have been used to treat localized tumors for decades. The discovery of the abscopal effect causes a paradigm shift where local therapy also causes systemic effects and leads to the remiss...