Invasive aspergillosis in liver transplant recipients: Epidemiology, clinical characteristics, treatment, and outcomes in 116 cases

• Published in: Liver transplantation Vol. 21; no. 2; pp. 204 - 212
• Main Authors: Barchiesi, Francesco, Mazzocato, Susanna, Mazzanti, Sara, Gesuita, Rosaria, Skrami, Edlira, Fiorentini, Alessandro, Singh, Nina
• Format: Journal Article
• Language: English
• Published: United States Wolters Kluwer Health, Inc 01.02.2015
• Subjects: Adult; Amphotericin B - therapeutic use; Aspergillosis - therapy; Aspergillus flavus; Aspergillus fumigatus; Cohort Studies; Female; Humans; Kaplan-Meier Estimate; Liver Failure - complications; Liver Failure - surgery; Liver Transplantation; Male; Middle Aged; Probability; Proportional Hazards Models; Renal Insufficiency - complications; Transplant Recipients; Treatment Outcome; Voriconazole - therapeutic use

Invasive aspergillosis (IA) in liver transplant recipients is associated with grave outcomes. We reviewed 116 individual cases reported in the literature from 1985 to 2013. IA was diagnosed after a median of 25 days after transplantation and involved a single organ in 51% of the cases, whereas in th...