Generation of a photocontrollable recombinant bovine parainfluenza virus type 3

• Published in: Microbiology and immunology Vol. 67; no. 4; p. 204
• Main Authors: Okura, Takashi, Tahara, Maino, Otsuki, Noriyuki, Sato, Moritoshi, Takeuchi, Kaoru, Takeda, Makoto
• Format: Journal Article
• Language: English
• Published: Australia 01.04.2023
• Subjects: Animals; Cattle; Cell Line; COVID-19; Humans; Parainfluenza Virus 3, Bovine - genetics; Parainfluenza Virus 3, Human - genetics; Respiratory Syncytial Virus, Human; Virus Replication; bovine parainfluenza virus type 3; Magnet system; reverse genetics; blue light illumination; Sendai virus; large protein; photocontrollable

Bovine parainfluenza virus type 3 (BPIV3) is a promising vaccine vector against various respiratory virus infections, including the human PIV3, respiratory syncytial virus, and severe acute respiratory syndrome-coronavirus 2 infections. In this study, we combined the Magnet system and reverse geneti...