An efficient approach for glomerular filtration rate assessment in older adults

• Published in: British journal of clinical pharmacology Vol. 78; no. 2; pp. 384 - 392
• Main Authors: Martus, Peter, Ebert, Natalie, Giet, Markus, Jakob, Olga, Schaeffner, Elke S.
• Format: Journal Article
• Language: English
• Published: England Blackwell Science Inc 01.08.2014
• Subjects: Aged; Aged, 80 and over; Anthropometry; Area Under Curve; Biomarkers - blood; Chromatography, High Pressure Liquid; Contrast Media - analysis; Creatinine - blood; Cross-Sectional Studies; cystatin C; Cystatin C - blood; Glomerular Filtration Rate; Humans; iohexol; Iohexol - analysis; kidney function; Mathematical Computing; Methods in Clinical Pharmacology Series; older adults; Renal Insufficiency, Chronic - blood; Renal Insufficiency, Chronic - diagnosis; Time Factors; older adults; cystatin C; iohexol; kidney function; glomerular filtration rate

Aims Assessment of glomerular filtration rate (GFR) is crucial because the GFR value defines the stage of chronic kidney disease and determines the adjustment of drug dosage. The aim was to investigate a new method for the accurate determination of GFR in older adults based on the combination of an...