Microstructural Anomalies Evaluated by Neurite Orientation Dispersion and Density Imaging Are Related to Deficits in Facial Emotional Recognition via Perceptual-Binding Difficulties in Autism Spectrum Disorder

• Published in: Autism research Vol. 13; no. 5; p. 729
• Main Authors: Yasuno, Fumihiko, Makinodan, Manabu, Takahashi, Masato, Matsuoka, Kiwamu, Yoshikawa, Hiroaki, Kitamura, Soichiro, Ishida, Rio, Kishimoto, Naoko, Miyasaka, Toshiteru, Kichikawa, Kimihiko, Kishimoto, Toshifumi
• Format: Journal Article
• Language: English
• Published: United States 01.05.2020
• Subjects: Adult; Autism Spectrum Disorder - physiopathology; Autism Spectrum Disorder - psychology; Brain - diagnostic imaging; Brain - physiopathology; Emotions; Facial Expression; Female; Humans; Magnetic Resonance Imaging - methods; Male; Neurites; Recognition, Psychology - physiology; Visual Perception - physiology; facial emotional recognition; interhemispheric; perceptual integration; neurite-orientation dispersion and density imaging; NODDI; corpus callosum; autism spectrum disorder

The integration of visual features is important for recognizing objects as a coherent whole, a key domain of difficulty in autism spectrum disorder (ASD). We tested the hypothesis that ASD patients exhibit difficulties in facial emotional recognition via perceptual binding difficulties due to weak c...