Asymmetric reactions of N-heterocyclic carbene (NHC)-based chiral acyl azoliums and azolium enolates

• Published in: Green synthesis and catalysis Vol. 2; no. 2; pp. 198 - 215
• Main Authors: Zhao, Changgui, Blaszczyk, Stephanie A., Wang, Jiaming
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.05.2021; KeAi Communications Co. Ltd
• Subjects: Acyl azoliums; Asymmetric synthesis; Enolates; N-Heterocyclic carbenes; Organocatalysis; Acyl azoliums; Asymmetric synthesis; N-Heterocyclic carbenes; Organocatalysis; Enolates

N-Heterocyclic carbene (NHC) organocatalysis has been recognized as a powerful synthetic strategy for the construction of a wide variety of medicinally and biologically important molecules. Although NHCs are known as the umpolung of aldehydes, NHC-based species involving non-umpolung processes have...