The chemistry and biology of guanidine secondary metabolites

Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal peptides, guanidine-bearing polyketides, alkaloids, terpenoids and shikimic acid derived, are the subject of this review. The...

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Published inNatural product reports Vol. 38; no. 3; pp. 586 - 667
Main Authors Berlinck, Roberto G. S., Bernardi, Darlon I., Fill, Taicia, Fernandes, Alessandra A. G., Jurberg, Igor D.
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 01.03.2021
Subjects
Amphibians
bioactive properties
Biological activity
Biosynthesis
Ecological function
Guanidine
guanidines
Invertebrates
Marine invertebrates
Marine microorganisms
Marine plants
mechanism of action
Metabolites
Microorganisms
Natural products
nonribosomal peptides
Peptides
Polyketides
Secondary metabolites
Shikimic acid
Spiders
Terpenes
terpenoids
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Summary:Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal peptides, guanidine-bearing polyketides, alkaloids, terpenoids and shikimic acid derived, are the subject of this review. The topics include the discovery of new metabolites, total synthesis of natural guanidine compounds, biological activity and mechanism-of-action, biosynthesis and ecological functions.
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ISSN:0265-0568
1460-4752
1460-4752
DOI:10.1039/D0NP00051E