Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes

• Published in: Briefings in bioinformatics Vol. 18; no. 6; pp. 984 - 992
• Main Authors: Xia, Siyu, Feng, Jing, Lei, Lijun, Hu, Jun, Xia, Linjian, Wang, Jun, Xiang, Yu, Liu, Lingjun, Zhong, Shan, Han, Leng, He, Chunjiang
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.11.2017; Oxford Publishing Limited (England)
• Subjects: brain; Circular RNA; Circularity; exons; Genomes; genomics; humans; mice; microRNA; miRNA; Polymerase chain reaction; reverse transcriptase polymerase chain reaction; Reverse transcription; RNA-binding protein; RNA-binding proteins; Tissues; tissue-specific; database; circRNA; RNAseq

Abstract Circular RNA (circRNA) is a group of RNA family generated by RNA circularization, which was discovered ubiquitously across different species and tissues. However, there is no global view of tissue specificity for circRNAs to date. Here we performed the comprehensive analysis to characterize...