Modulation of Fecal Clostridiales Bacteria and Butyrate by Probiotic Intervention with Lactobacillus paracasei DG Varies among Healthy Adults

• Published in: The Journal of nutrition Vol. 144; no. 11; pp. 1787 - 1796
• Main Authors: Ferrario, Chiara, Taverniti, Valentina, Milani, Christian, Fiore, Walter, Laureati, Monica, De Noni, Ivano, Stuknyte, Milda, Chouaia, Bessem, Riso, Patrizia, Guglielmetti, Simone
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2014
• Subjects: Adult; Butyric Acid - chemistry; Butyric Acid - metabolism; Double-Blind Method; Feces - chemistry; Feces - microbiology; Female; Gram-Positive Endospore-Forming Rods - classification; Gram-Positive Endospore-Forming Rods - isolation & purification; Humans; Lactobacillus; Life Sciences; Male; Middle Aged; Probiotics; Young Adult; HB; IBS; LB; PLS; rRNA

The modulation of gut microbiota is considered to be the first target to establish probiotic efficacy in a healthy population. This study was conducted to determine the impact of a probiotic on the intestinal microbial ecology of healthy volunteers. High-throughput 16S ribosomal RNA gene sequencing...