CTCF inhibits endoplasmic reticulum stress and apoptosis in cardiomyocytes by upregulating RYR2 via inhibiting S100A1 - Zeng, Zhu; Huang, Nina; Zhang, Yudan; Wang, Ying; Su, Yufei; Zhang, Huifang; An, Yuan (Life sciences (1973), 2020)
Keywords: Adolescent; Animals; Annexin V; Apoptosis; Apoptosis - physiology; Blood; Blotting, Western; Cardiomyocytes; Cardiovascular diseases; CCCTC-binding factor; CCCTC-Binding Factor - metabolism; CCCTC-Binding Factor - physiology; Child; Child, Preschool; Children; Congestive heart failure; Endoplasmic reticulum; Endoplasmic reticulum stress; Endoplasmic Reticulum Stress - physiology; Enzyme-Linked Immunosorbent Assay; Female; Heart failure; Heart Failure - metabolism; Heart Failure - physiopathology; Humans; Immunoprecipitation; Male; Mice; Myocytes, Cardiac - drug effects; Myocytes, Cardiac - metabolism; Pediatrics; precipitin tests; quantitative polymerase chain reaction; Real-Time Polymerase Chain Reaction; repressor proteins; Ryanodine Receptor Calcium Release Channel - metabolism; Ryanodine Receptor Calcium Release Channel - physiology; Ryanodine receptors; S100 Proteins - metabolism; S100 Proteins - physiology; Signal transduction; Therapeutic applications; therapeutics; Tunicamycin; Up-Regulation; Western blotting; Cardiomyocytes; CCCTC-binding factor; Apoptosis; Endoplasmic reticulum stress