Visualizing tumour self-homing with magnetic particle imaging

• Published in: Nanoscale Vol. 13; no. 12; pp. 616 - 623
• Main Authors: Parkins, Katie M, Melo, Kierstin P, Chen, Yuanxin, Ronald, John A, Foster, Paula J
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 28.03.2021
• Subjects: Animals; Breast Neoplasms - diagnostic imaging; Diagnostic Imaging; Genes; Genes, Reporter; Homing; Humans; Imaging; Iron; Iron oxides; Magnetic Phenomena; Magnetic Resonance Imaging; Mice; Neoplastic Cells, Circulating; Positron emission; Tomography; Transplantation; Tumors

Due to their innate tumour homing capabilities, in recent years, circulating tumour cells (CTCs) have been engineered to express therapeutic genes for targeted treatment of primary and metastatic lesions. Additionally, previous studies have incorporated optical or PET imaging reporter genes to enabl...