Pathogenesis of Hendra and Nipah virus infection in humans

• Published in: Journal of infection in developing countries Vol. 7; no. 4; pp. 308 - 311
• Main Authors: Escaffre, Olivier, Borisevich, Viktoriya, Rockx, Barry
• Format: Journal Article
• Language: English
• Published: Italy Journal of Infection in Developing Countries 01.04.2013; The Journal of Infection in Developing Countries
• Subjects: Animals; Blood-Brain Barrier - immunology; Blood-Brain Barrier - virology; central nervous system; Hendra; Hendra Virus - immunology; Hendra Virus - pathogenicity; Henipavirus Infections - immunology; Henipavirus Infections - transmission; Humans; Infections; Interleukin-1beta - immunology; Lung - pathology; Lung - virology; Neurons - immunology; Neurons - virology; Nipah; Nipah Virus - immunology; Nipah Virus - pathogenicity; Pathogenesis; Respiratory Mucosa - virology; respiratory tract; Viremia - pathology; Virus Internalization; Viruses; zoonotic

Hendra virus (HeV) and Nipah virus (NiV) are emerging zoonotic viruses that cause severe and often lethal respiratory illness and encephalitis in humans. Henipaviruses can infect a wide range of species and human-to-human transmission has been observed for NiV. While the exact route of transmission...