SGLT2 Inhibition, Choline Metabolites, and Cardiometabolic Diseases: A Mediation Mendelian Randomization Study - Xu, Min; Zheng, Jie; Hou, Tianzhichao; Lin, Hong; Wang, Tiange; Wang, Shuangyuan; Lu, Jieli; Zhao, Zhiyun; Li, Mian; Xu, Yu; Ning, Guang; Bi, Yufang; et al. (Diabetes care, 2022)
Keywords: Cardiovascular disease; Choline; Coronary artery; Coronary artery disease; Coronary Artery Disease - genetics; Coronary vessels; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - metabolism; Gene expression; Genetics; Genome-Wide Association Study - methods; Genomes; Glycine; Glycine - genetics; Heart diseases; Hemoglobin; Humans; Inhibition; Lecithin; Mendelian Randomization Analysis - methods; Meta-analysis; Metabolites; Na+/glucose cotransporter; Phosphatidylcholine; Phosphatidylcholines; Polymorphism, Single Nucleotide; Randomization; Replication; Research design; Risk Factors; Sodium-Glucose Transporter 2 Inhibitors - therapeutic use; Statistical analysis; Vein & artery diseases