Diagnostic Value of Free Prostate-Specific Antigen among Men with a Prostate-Specific Antigen Level of <3.0μg per Liter

• Published in: European urology Vol. 54; no. 2; pp. 362 - 370
• Main Authors: Finne, Patrik, Auvinen, Anssi, Määttänen, Liisa, Tammela, Teuvo L., Ruutu, Mirja, Juusela, Harri, Martikainen, Paula, Hakama, Matti, Stenman, Ulf-Håkan
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.08.2008
• Subjects: Free PSA; Prostate cancer screening; Total PSA; Urology; Prostate cancer screening; Total PSA; Free PSA

The percentage of free prostate-specific antigen (%fPSA) improves the diagnostic accuracy for prostate cancer when the serum level of total PSA (tPSA) is elevated. Approximately 14% of men with a tPSA below 3μg/l have prostate cancer on biopsy, but the diagnostic value of %fPSA in such men is rather...