Rhus verniciflua leaf extract suppresses obesity in high-fat diet-induced obese mice
Obesity is a serious health problem in the world. We thought that the activity and safety of natural plants and/or foods are very important in the management of therapy for obesity. ( ) is also known as lacquer tree in Japan and Korea, and it is consumed as food ingredients and/or traditional herbal...
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Published in | Food & nutrition research Vol. 63; pp. 1 - 9 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Sweden
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11.09.2019
Swedish Nutrition Foundation |
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Abstract | Obesity is a serious health problem in the world. We thought that the activity and safety of natural plants and/or foods are very important in the management of therapy for obesity.
(
) is also known as lacquer tree in Japan and Korea, and it is consumed as food ingredients and/or traditional herbal medicine. We prepared an extract from
leaves (Rv-PEM01-99) to develop a new functional food material and/or nutritional supplements.
This study evaluated the anti-obesity effects of the Rv-PEM01-99 in high-fat diet (HFD)-induced obese mice.
Six-week-old male C57BL/6J mice were divided into three groups: group I (HFD group), group II (HFD + 1% Rv-PEM01-99 group), and group III (HFD + 2% Rv-PEM01-99 group). Throughout the 56-day treatment period, body weights of these mice were checked twice a week. After 56 days, blood biochemical analyses were performed.
In animal studies, no death or abnormalities in food consumption were observed between groups I, II, and III. Body weight gain in the groups administered Rv-PEM01-99 was less than that in group I. In particular, body weight gain in group III was significantly less than that in group I after 52 days of Rv-PEM01-99 administration. In addition, intra-abdominal fat and leptin levels in group III were significantly lower than those in group I. HPLC and LC/MS analysis showed a quercetin derivative as an active compound in Rv-PEM01-99.
Rv-PEM01-99, containing a quercetin derivative, showed anti-obesity effect in HFD-fed mice. It could therefore be useful as food material and/or nutritional supplement for management of obesity. |
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AbstractList | BACKGROUNDObesity is a serious health problem in the world. We thought that the activity and safety of natural plants and/or foods are very important in the management of therapy for obesity. Rhus verniciflua (R. verniciflua) is also known as lacquer tree in Japan and Korea, and it is consumed as food ingredients and/or traditional herbal medicine. We prepared an extract from R. verniciflua leaves (Rv-PEM01-99) to develop a new functional food material and/or nutritional supplements. OBJECTIVEThis study evaluated the anti-obesity effects of the Rv-PEM01-99 in high-fat diet (HFD)-induced obese mice. DESIGNSix-week-old male C57BL/6J mice were divided into three groups: group I (HFD group), group II (HFD + 1% Rv-PEM01-99 group), and group III (HFD + 2% Rv-PEM01-99 group). Throughout the 56-day treatment period, body weights of these mice were checked twice a week. After 56 days, blood biochemical analyses were performed. RESULTSIn animal studies, no death or abnormalities in food consumption were observed between groups I, II, and III. Body weight gain in the groups administered Rv-PEM01-99 was less than that in group I. In particular, body weight gain in group III was significantly less than that in group I after 52 days of Rv-PEM01-99 administration. In addition, intra-abdominal fat and leptin levels in group III were significantly lower than those in group I. HPLC and LC/MS analysis showed a quercetin derivative as an active compound in Rv-PEM01-99. CONCLUSIONRv-PEM01-99, containing a quercetin derivative, showed anti-obesity effect in HFD-fed mice. It could therefore be useful as food material and/or nutritional supplement for management of obesity. Obesity is a serious health problem in the world. We thought that the activity and safety of natural plants and/or foods are very important in the management of therapy for obesity. ( ) is also known as lacquer tree in Japan and Korea, and it is consumed as food ingredients and/or traditional herbal medicine. We prepared an extract from leaves (Rv-PEM01-99) to develop a new functional food material and/or nutritional supplements. This study evaluated the anti-obesity effects of the Rv-PEM01-99 in high-fat diet (HFD)-induced obese mice. Six-week-old male C57BL/6J mice were divided into three groups: group I (HFD group), group II (HFD + 1% Rv-PEM01-99 group), and group III (HFD + 2% Rv-PEM01-99 group). Throughout the 56-day treatment period, body weights of these mice were checked twice a week. After 56 days, blood biochemical analyses were performed. In animal studies, no death or abnormalities in food consumption were observed between groups I, II, and III. Body weight gain in the groups administered Rv-PEM01-99 was less than that in group I. In particular, body weight gain in group III was significantly less than that in group I after 52 days of Rv-PEM01-99 administration. In addition, intra-abdominal fat and leptin levels in group III were significantly lower than those in group I. HPLC and LC/MS analysis showed a quercetin derivative as an active compound in Rv-PEM01-99. Rv-PEM01-99, containing a quercetin derivative, showed anti-obesity effect in HFD-fed mice. It could therefore be useful as food material and/or nutritional supplement for management of obesity. Background: Obesity is a serious health problem in the world. We thought that the activity and safety of natural plants and/or foods are very important in the management of therapy for obesity. Rhus verniciflua (R. verniciflua) is also known as lacquer tree in Japan and Korea, and it is consumed as food ingredients and/or traditional herbal medicine. We prepared an extract from R. verniciflua leaves (Rv-PEM01-99) to develop a new functional food material and/or nutritional supplements. Objective: This study evaluated the anti-obesity effects of the Rv-PEM01-99 in high-fat diet (HFD)-induced obese mice. Design: Six-week-old male C57BL/6J mice were divided into three groups: group I (HFD group), group II (HFD + 1% Rv-PEM01-99 group), and group III (HFD + 2% Rv-PEM01-99 group). Throughout the 56-day treatment period, body weights of these mice were checked twice a week. After 56 days, blood biochemical analyses were performed. Results: In animal studies, no death or abnormalities in food consumption were observed between groups I, II, and III. Body weight gain in the groups administered Rv-PEM01-99 was less than that in group I. In particular, body weight gain in group III was significantly less than that in group I after 52 days of Rv-PEM01-99 administration. In addition, intra-abdominal fat and leptin levels in group III were significantly lower than those in group I. HPLC and LC/MS analysis showed a quercetin derivative as an active compound in Rv-PEM01-99. Conclusion: Rv-PEM01-99, containing a quercetin derivative, showed anti-obesity effect in HFD-fed mice. It could therefore be useful as food material and/or nutritional supplement for management of obesity. |
Author | Arai, Toshiro Tomita, Tsuyoshi Suruga, Kohei Kadokura, Kazunari |
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Cites_doi | 10.1007/sl1064-008-9861-z 10.1016/S0140-6736(05)67483-1 10.1186/1475-2891-9-3 10.4236/oji.2015.51005 10.5530/fra.2015.2.7 10.1111/j.1365-2621.2010.02287.x 10.1038/oby.2008.242 10.1055/s-0042-113458 10.4236/jct.2016.77048 10.5897/JMPR/E52792F18942 10.1016/S2213-8587(17)30236-X 10.1016/S0014-2999(02)01422-X 10.1021/jf071225x 10.3177/jnsv.56.150 10.2337/diab.37.12.1595 10.1161/01.ATV.0000216787.85457.f3 10.1007/s11418-014-0871-7 10.3389/fnut.2018.00074 10.1016/S0140-6736(10)62037-5 10.1016/j.ijbiomac.2012.09.009 10.1002/oby.20416 10.1023/A:1011808701117 https://www.researchgate.net/publication/281313923 10.1093/ecam/neh004 10.1016/S0021-9673(01)87848-1 10.1016/j.foodchem.2009.10.051 10.1034/j.1600-079X.2002.20920.x 10.1001/jama.282.16.1568 10.3858/emm.2010.42.9.062 10.1007/s11130-007-0058-4 10.1007/978-3-642-78759-1_35 10.3177/jnsv.53.267 10.1017/S0954422418000082 10.1007/BF02975339 10.1111/j.2042-7158.2011.01342.x 10.1097/MED.0000000000000184 10.1056/NEJMoa1808721 |
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Keywords | quercetin derivative plant extract anti-obesity |
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References | Vogel (cit0012) 1994; 3 Gentile (cit0011) 2018; 31 Kiyohara (cit0021) 2004; 1 Gulcin (cit0008) 2002; 3 Basemen (cit0025) 2018; 6 Heymsfield (cit0036) 1999; 282 Du (cit0022) 1984; 248 Ballinger (cit0023) 2002; 440 Hong (cit0015) 1999; 22 10 Facts on obesity (cit0003) 2019 Halliwell (cit0007) 1989 Song (cit0014) 2010; 42 Hiruma (cit0017) 2015; 5 Miyata (cit0032) 2010; 56 Rayne (cit0030) 2007; 62 Farr (cit0035) 2015; 22 Clement Vicario (cit0019) 2016; 7 Poirier (cit0004) 2006; 26 Carlsen (cit0010) 2010; 9 Panat (cit0040) 2015; 5 Han (cit0009) 2013; 2 Kadokura (cit0020) 2015; 69 Bray (cit0028) 2001; 2 Pereira (cit0038) 2009; 34 Reaven (cit0034) 1988; 37 Haslam (cit0005) 2005; 366 Maguire (cit0006) 2010 Kawasumi (cit0033) 2018; 5 Mai (cit0029) 2007; 53 Kim (cit0031) 2011; 5 Overweight and obesity (cit0002) 2019 Shirouchi (cit0027) 2008; 55 Kim (cit0016) 2011; 63 Bohula (cit0024) 2018; 379 Morisset (cit0026) 2008; 16 Suruga (cit0018) 2017; 65 Liu (cit0037) 2013; 21 Kim (cit0013) 2010; 120 Finucane (cit0001) 2011; 377 Bose (cit0039) 2013; 2 |
References_xml | – volume: 34 start-page: 973 year: 2009 ident: cit0038 publication-title: Neurochem Res doi: 10.1007/sl1064-008-9861-z contributor: fullname: Pereira – volume: 366 start-page: 1197 year: 2005 ident: cit0005 publication-title: Lancet doi: 10.1016/S0140-6736(05)67483-1 contributor: fullname: Haslam – volume: 9 start-page: 3 year: 2010 ident: cit0010 publication-title: Nutr J doi: 10.1186/1475-2891-9-3 contributor: fullname: Carlsen – volume: 5 start-page: 39 year: 2015 ident: cit0017 publication-title: Open J Immunol doi: 10.4236/oji.2015.51005 contributor: fullname: Hiruma – volume: 5 start-page: 90 year: 2015 ident: cit0040 publication-title: Free Rad Antiox doi: 10.5530/fra.2015.2.7 contributor: fullname: Panat – start-page: 264 year: 2010 ident: cit0006 publication-title: The obesity epidemic and its management doi: 10.1111/j.1365-2621.2010.02287.x contributor: fullname: Maguire – volume: 16 start-page: 1487 year: 2008 ident: cit0026 publication-title: Obesity doi: 10.1038/oby.2008.242 contributor: fullname: Morisset – volume: 65 start-page: 127 year: 2017 ident: cit0018 publication-title: Drug Res doi: 10.1055/s-0042-113458 contributor: fullname: Suruga – volume: 7 start-page: 464 year: 2016 ident: cit0019 publication-title: J Cancer Ther doi: 10.4236/jct.2016.77048 contributor: fullname: Clement Vicario – volume: 5 start-page: 778 year: 2011 ident: cit0031 publication-title: J Med Plants Res doi: 10.5897/JMPR/E52792F18942 contributor: fullname: Kim – volume: 6 start-page: 237 year: 2018 ident: cit0025 publication-title: Lancet Diabetes Endocrinol doi: 10.1016/S2213-8587(17)30236-X contributor: fullname: Basemen – volume: 440 start-page: 109 year: 2002 ident: cit0023 publication-title: Eur J Pharmacol doi: 10.1016/S0014-2999(02)01422-X contributor: fullname: Ballinger – volume: 55 start-page: 7170 year: 2008 ident: cit0027 publication-title: J Agric Food Chem doi: 10.1021/jf071225x contributor: fullname: Shirouchi – volume: 56 start-page: 150 year: 2010 ident: cit0032 publication-title: J Nutr Sci Vitaminol doi: 10.3177/jnsv.56.150 contributor: fullname: Miyata – volume: 37 start-page: 1595 year: 1988 ident: cit0034 publication-title: Diabetes doi: 10.2337/diab.37.12.1595 contributor: fullname: Reaven – year: 2019 ident: cit0002 publication-title: Overweight and obesity contributor: fullname: Overweight and obesity – volume: 26 start-page: 968 year: 2006 ident: cit0004 publication-title: Arterioscler Thromb Vasc Biol doi: 10.1161/01.ATV.0000216787.85457.f3 contributor: fullname: Poirier – volume: 69 start-page: 148 year: 2015 ident: cit0020 publication-title: J Natl Med doi: 10.1007/s11418-014-0871-7 contributor: fullname: Kadokura – volume: 5 start-page: 74 year: 2018 ident: cit0033 publication-title: Front Nutr doi: 10.3389/fnut.2018.00074 contributor: fullname: Kawasumi – volume: 377 start-page: 557 year: 2011 ident: cit0001 publication-title: Lancet doi: 10.1016/S0140-6736(10)62037-5 contributor: fullname: Finucane – volume: 2 start-page: 66 year: 2013 ident: cit0009 publication-title: Int J Biol Macromol doi: 10.1016/j.ijbiomac.2012.09.009 contributor: fullname: Han – volume: 21 start-page: 1991 year: 2013 ident: cit0037 publication-title: Obesity doi: 10.1002/oby.20416 contributor: fullname: Liu – volume: 2 start-page: 403 year: 2001 ident: cit0028 publication-title: Rev Endocr Metab Disord doi: 10.1023/A:1011808701117 contributor: fullname: Bray – volume: 2 start-page: 72 year: 2013 ident: cit0039 publication-title: J Pharma Sci Tech doi: https://www.researchgate.net/publication/281313923 contributor: fullname: Bose – year: 2019 ident: cit0003 publication-title: 10 Facts on obesity contributor: fullname: 10 Facts on obesity – volume: 1 start-page: 83 year: 2004 ident: cit0021 publication-title: Evid Based Complement Alternat Med doi: 10.1093/ecam/neh004 contributor: fullname: Kiyohara – volume: 248 start-page: 463 year: 1984 ident: cit0022 publication-title: J Chromatogr doi: 10.1016/S0021-9673(01)87848-1 contributor: fullname: Du – volume: 120 start-page: 539 year: 2010 ident: cit0013 publication-title: Food Chem doi: 10.1016/j.foodchem.2009.10.051 contributor: fullname: Kim – start-page: 20 year: 1989 ident: cit0007 publication-title: Free radicals in biology and medicine contributor: fullname: Halliwell – volume: 3 start-page: 167 year: 2002 ident: cit0008 publication-title: J Pineal Res doi: 10.1034/j.1600-079X.2002.20920.x contributor: fullname: Gulcin – volume: 282 start-page: 1568 year: 1999 ident: cit0036 publication-title: JAMA doi: 10.1001/jama.282.16.1568 contributor: fullname: Heymsfield – volume: 42 start-page: 628 year: 2010 ident: cit0014 publication-title: Exp Mol Med doi: 10.3858/emm.2010.42.9.062 contributor: fullname: Song – volume: 62 start-page: 165 year: 2007 ident: cit0030 publication-title: Plant Foods Hum Nutr doi: 10.1007/s11130-007-0058-4 contributor: fullname: Rayne – volume: 3 start-page: 423 year: 1994 ident: cit0012 publication-title: Oriental lacquer. Progress in pacific polymer science doi: 10.1007/978-3-642-78759-1_35 contributor: fullname: Vogel – volume: 53 start-page: 267 year: 2007 ident: cit0029 publication-title: J Nutr Sci Vitaminol doi: 10.3177/jnsv.53.267 contributor: fullname: Mai – volume: 31 start-page: 239 year: 2018 ident: cit0011 publication-title: Nutr Res Rev doi: 10.1017/S0954422418000082 contributor: fullname: Gentile – volume: 22 start-page: 638 year: 1999 ident: cit0015 publication-title: Arch Pharm Res doi: 10.1007/BF02975339 contributor: fullname: Hong – volume: 63 start-page: 1358 year: 2011 ident: cit0016 publication-title: J Pharm Pharmacol doi: 10.1111/j.2042-7158.2011.01342.x contributor: fullname: Kim – volume: 22 start-page: 353 year: 2015 ident: cit0035 publication-title: Curr Opin Endocrinol Diabetes Obes doi: 10.1097/MED.0000000000000184 contributor: fullname: Farr – volume: 379 start-page: 1107 year: 2018 ident: cit0024 publication-title: N Engl J Med doi: 10.1056/NEJMoa1808721 contributor: fullname: Bohula |
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Title | Rhus verniciflua leaf extract suppresses obesity in high-fat diet-induced obese mice |
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