Rapid prenatal diagnostic testing for Down syndrome only or longer wait for full karyotype: the views of pregnant women

• Published in: Prenatal diagnosis Vol. 25; no. 13; pp. 1206 - 1211
• Main Authors: Ryan, Mandy, Diack, Jane, Watson, Verity, Smith, Norman
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.12.2005; Wiley
• Subjects: Adolescent; Adult; Amniocentesis; Biological and medical sciences; Chromosome aberrations; Chromosome Aberrations - embryology; discrete choice experiments; Down Syndrome - diagnosis; Female; Gynecology. Andrology. Obstetrics; Humans; Karyotyping - methods; Management. Prenatal diagnosis; Medical genetics; Medical sciences; Patient Acceptance of Health Care - psychology; Pilot Projects; Pregnancy; Pregnancy. Fetus. Placenta; Prenatal Diagnosis - economics; rapid prenatal diagnosis; Surveys and Questionnaires; Time Factors; willingness to pay; Chromosomal aberration; Human; Trisomy; willingness to pay; Choice; Prenatal Diagnosis; Chromosome G21; Aneuploidy; Duration; Down syndrome; Medical screening; Pregnancy; Prenatal; discrete choice experiments; Cytogenetics; Adult; Female; rapid prenatal diagnosis; Expectation; Karyotype

Objectives Prenatal diagnosis by karyotype analysis determines the copy number and structure of each chromosome and is considered to be the ‘gold standard’ in detection of chromosome abnormality. This method is, however, time consuming and women may have to wait up to 21 days for the results. With i...