Low‐dose aspirin reduces uteroplacental vascular impedance in early and mid gestation in IVF and ICSI patients: a randomized, placebo‐controlled double‐blind study

• Published in: Ultrasound in obstetrics & gynecology Vol. 32; no. 5; pp. 687 - 693
• Main Authors: Haapsamo, M., Martikainen, H., Räsänen, J.
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.10.2008; Wiley
• Subjects: Adult; Arteries - physiology; Aspirin - administration & dosage; Aspirin - pharmacokinetics; assisted reproduction; Biological and medical sciences; Blood Flow Velocity - physiology; Bones, joints and connective tissue. Antiinflammatory agents; Cardiovascular system; Doppler ultrasonography; Double-Blind Method; Female; Fibrinolytic Agents - administration & dosage; Fibrinolytic Agents - pharmacology; Gynecology. Andrology. Obstetrics; Humans; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Ovulation Induction - methods; Pharmacology. Drug treatments; placenta; Placenta - blood supply; Pregnancy; Pregnancy Trimester, Second; Pulsatile Flow - physiology; Sperm Injections, Intracytoplasmic - methods; Ultrasonic investigative techniques; uteroplacental hemodynamics; Uterus - blood supply; Doppler ultrasound study; Prostaglandin-endoperoxide synthase; Doppler ultrasonography; Assisted procreation; Acetylsalicylic acid; Randomization; assisted reproduction; Blood vessel; Clinical trial; Salicylates; Sonography; Human; uteroplacental hemodynamics; Enzyme; Intracytoplasmic sperm injection; Low dose; Gynecology; Enzyme inhibitor; Obstetrics; Antiplatelet agent; Non steroidal antiinflammatory agent; In vitro fertilization embryo transfer; Pregnancy; Analgesic; Placenta; Antipyretic; Double blind study; Early; Oxidoreductases; Hemodynamics; Impedance

Objective To determine whether low‐dose aspirin improves uteroplacental hemodynamics in unselected in‐vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) subjects when medication is started concomitantly with controlled ovarian hyperstimulation. Methods Thirty‐seven pregnant women who ha...