Prevalence and significance of HER‐2/neu expression in early epithelial ovarian cancer

• Published in: Cancer Vol. 73; no. 5; pp. 1456 - 1459
• Main Authors: Rubin, Stephen C., Finstad, Connie L., Federici, Mark G., Scheiner, Linda, Lloyd, Kenneth O., Hoskins, William J.
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 01.03.1994; Wiley-Liss
• Subjects: Adult; Aged; Biological and medical sciences; Biomarkers, Tumor - analysis; Female; Female genital diseases; Gene Expression Regulation, Neoplastic; Gynecology. Andrology. Obstetrics; HER‐2/neu, prognosis; Humans; Medical sciences; Middle Aged; Neoplasm Staging; oncogene; Oncogene Proteins, Viral - analysis; ovarian cancer; Ovarian Neoplasms - genetics; Ovarian Neoplasms - mortality; Prognosis; Receptor, ErbB-2; Tumors; Human; Ovarian diseases; Ovary; Carcinoma; Prognosis; Prevalence; Female; Malignant tumor; Onc gene; Protooncogene; Female genital diseases

Background. Although expression of the HER‐2/neu oncogene may be of some prognostic importance in advanced ovarian cancer, its role in early‐stage disease has not been established. The current study examined the prevalence and significance of HER‐2/neu expression in early epithelial ovarian cancer....