Cadmium-Induced Renal Cell Toxicity Is Associated With MicroRNA Deregulation

• Published in: International journal of toxicology Vol. 39; no. 2; p. 103
• Main Authors: Lemaire, J, Van der Hauwaert, C, Savary, G, Dewaeles, E, Perrais, M, Lo Guidice, J M, Pottier, N, Glowacki, F, Cauffiez, C
• Format: Journal Article
• Language: English
• Published: United States 01.03.2020
• Subjects: Cadmium - toxicity; Cell Line; Cell Survival - drug effects; Epithelial Cells - drug effects; Epithelial Cells - metabolism; Humans; Kidney - cytology; MicroRNAs - metabolism; nephrotoxicity; cadmium; microRNA

Cadmium is an environmental pollutant well known for its nephrotoxic effects. Nevertheless, mechanisms underlying nephrotoxicity continue to be elucidated. MicroRNAs (miRNAs) have emerged in recent years as modulators of xenobiotic-induced toxicity. In this context, our study aimed at elucidating wh...