Antiphospholipid antibody-related hepatic vasculitis in a juvenile after non-severe COVID-19: a case report and literature review

• Published in: Frontiers in immunology Vol. 15; p. 1354349
• Main Authors: Li, Qingyu, Li, Jingya, Zhou, Menglan, Ge, Ying, Liu, Zhengyin, Li, Taisheng, Zhang, Li
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 2024
• Subjects: Adolescent; Antibodies, Antiphospholipid - blood; Antibodies, Antiphospholipid - immunology; antiphospholipid antibodies; Antiphospholipid Syndrome - complications; Antiphospholipid Syndrome - immunology; COVID-19; COVID-19 - complications; COVID-19 - immunology; Female; Humans; Liver - pathology; non-thrombotic manifestation; pediatrics; SARS-CoV-2 - immunology; vasculitis; Vasculitis - etiology; Vasculitis - immunology; vasculopathy; COVID-19; non-thrombotic manifestation; vasculopathy; vasculitis; antiphospholipid antibodies; pediatrics

Antiphospholipid antibodies (aPL) are both laboratory evidence and causative factors for a broad spectrum of clinical manifestations of antiphospholipid syndrome (APS), with thrombotic and obstetric events being the most prevalent. Despite the aPL-triggered vasculopathy nature of APS, vasculitic-lik...