Glutamate receptor genetic variants affected peripheral glutamatergic transmission and treatment induced improvement of Indian ADHD probands

• Published in: Scientific reports Vol. 13; no. 1; pp. 19922 - 14
• Main Authors: Chatterjee, Mahasweta, Saha, Sharmistha, Shom, Sayanti, Dutta, Nilanjana, Sinha, Swagata, Mukhopadhyay, Kanchan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 14.11.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 631/208; 631/337; 631/378; 631/61; 692/308; 692/4017; 692/53; 692/699; Attention deficit hyperactivity disorder; Children; Gene expression; Genetic diversity; Genetic variance; Genotypes; Glutamate receptors; Glutamatergic transmission; Humanities and Social Sciences; Methylphenidate; multidisciplinary; Peripheral blood; Science; Science (multidisciplinary)

Attention deficit hyperactivity disorder (ADHD), a childhood-onset neurobehavioral disorder, often perturbs scholastic achievement and peer-relationship. The pivotal role of glutamate (Glu) in learning and memory indicated an influence of Glu in ADHD, leading to the exploration of Glu in different b...