A recognition survey of granular corneal dystrophy type 2 genetic detection in China
To evaluate the feasibility of promoting genetic detection for granular corneal dystrophy type 2 (GCD ) by a questionnaire conducted among citizens in five cities in China. The data were collected by questionnaire, and analyzed by Chi-square test and one-tailed test in IBM SPSS statistics. Based on...
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Published in | International journal of ophthalmology Vol. 13; no. 12; pp. 1976 - 1982 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
China
International Journal of Ophthalmology Press
18.12.2020
Press of International Journal of Ophthalmology (IJO PRESS) |
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Abstract | To evaluate the feasibility of promoting genetic detection for granular corneal dystrophy type 2 (GCD
) by a questionnaire conducted among citizens in five cities in China.
The data were collected by questionnaire, and analyzed by Chi-square test and one-tailed
test in IBM SPSS statistics.
Based on the survey data on the awareness of GCD
genetic detection in this study and the positive predictive analysis report of the citizens in five cities in China, the vast majority (84.2%) of respondents had never heard of it and did not know that GCD
patients have been prohibited from performing excimer surgery that can deteriorate GCD
patients' condition even leading to blindness. Though 3.4% of patients understood GCD
very much, they have no idea that GCD
could not be 100% accuracy diagnosed by the conventional inspection methods.
It is feasible and necessary to use GCD
genetic detection as an excimer preoperative examination project. In order to promote the development of detection project, a few improvements should be carried out in terms of the promoting efforts, costs, and research progress. |
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AbstractList | To evaluate the feasibility of promoting genetic detection for granular corneal dystrophy type 2 (GCD
) by a questionnaire conducted among citizens in five cities in China.
The data were collected by questionnaire, and analyzed by Chi-square test and one-tailed
test in IBM SPSS statistics.
Based on the survey data on the awareness of GCD
genetic detection in this study and the positive predictive analysis report of the citizens in five cities in China, the vast majority (84.2%) of respondents had never heard of it and did not know that GCD
patients have been prohibited from performing excimer surgery that can deteriorate GCD
patients' condition even leading to blindness. Though 3.4% of patients understood GCD
very much, they have no idea that GCD
could not be 100% accuracy diagnosed by the conventional inspection methods.
It is feasible and necessary to use GCD
genetic detection as an excimer preoperative examination project. In order to promote the development of detection project, a few improvements should be carried out in terms of the promoting efforts, costs, and research progress. AIM: To evaluate the feasibility of promoting genetic detection for granular corneal dystrophy type 2 (GCD2) by a questionnaire conducted among citizens in five cities in China. METHODS: The data were collected by questionnaire, and analyzed by Chi-square test and one-tailed t test in IBM SPSS statistics. RESULTS: Based on the survey data on the awareness of GCD2 genetic detection in this study and the positive predictive analysis report of the citizens in five cities in China, the vast majority (84.2%) of respondents had never heard of it and did not know that GCD2 patients have been prohibited from performing excimer surgery that can deteriorate GCD2 patients’ condition even leading to blindness. Though 3.4% of patients understood GCD2 very much, they have no idea that GCD2 could not be 100% accuracy diagnosed by the conventional inspection methods. CONCLUSION: It is feasible and necessary to use GCD2 genetic detection as an excimer preoperative examination project. In order to promote the development of detection project, a few improvements should be carried out in terms of the promoting efforts, costs, and research progress. AIM: To evaluate the feasibility of promoting genetic detection for granular corneal dystrophy type 2 (GCD2) by a questionnaire conducted among citizens in five cities in China. METHODS: The data were collected by questionnaire, and analyzed by Chi-square test and one-tailed t test in IBM SPSS statistics. RESULTS: Based on the survey data on the awareness of GCD2 genetic detection in this study and the positive predictive analysis report of the citizens in five cities in China, the vast majority (84.2%) of respondents had never heard of it and did not know that GCD2 patients have been prohibited from performing excimer surgery that can deteriorate GCD2 patients’ condition even leading to blindness. Though 3.4% of patients understood GCD2 very much, they have no idea that GCD2 could not be 100% accuracy diagnosed by the conventional inspection methods. CONCLUSION: It is feasible and necessary to use GCD2 genetic detection as an excimer preoperative examination project. In order to promote the development of detection project, a few improvements should be carried out in terms of the promoting efforts, costs, and research progress. AIMTo evaluate the feasibility of promoting genetic detection for granular corneal dystrophy type 2 (GCD2) by a questionnaire conducted among citizens in five cities in China. METHODSThe data were collected by questionnaire, and analyzed by Chi-square test and one-tailed t test in IBM SPSS statistics. RESULTSBased on the survey data on the awareness of GCD2 genetic detection in this study and the positive predictive analysis report of the citizens in five cities in China, the vast majority (84.2%) of respondents had never heard of it and did not know that GCD2 patients have been prohibited from performing excimer surgery that can deteriorate GCD2 patients' condition even leading to blindness. Though 3.4% of patients understood GCD2 very much, they have no idea that GCD2 could not be 100% accuracy diagnosed by the conventional inspection methods. CONCLUSIONIt is feasible and necessary to use GCD2 genetic detection as an excimer preoperative examination project. In order to promote the development of detection project, a few improvements should be carried out in terms of the promoting efforts, costs, and research progress. |
Author | Wang, Ya-Duan Zheng, Qing-Mei Song, Xuan Wang, He Zhang, Nan-Wen Zhou, Bi-Ting Chen, Xiao-Le Zhu, Yi-Hua Wang, Xin-Rui Huang, Qiu-Kai Yang, Ju-Hua |
AuthorAffiliation | 3 School of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, Fujian Province, China 1 Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China 2 Department of Ophthalmology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350122, Fujian Province, China |
AuthorAffiliation_xml | – name: 3 School of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, Fujian Province, China – name: 2 Department of Ophthalmology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350122, Fujian Province, China – name: 1 Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China |
Author_xml | – sequence: 1 givenname: Xin-Rui surname: Wang fullname: Wang, Xin-Rui organization: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China – sequence: 2 givenname: Bi-Ting surname: Zhou fullname: Zhou, Bi-Ting organization: Department of Ophthalmology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350122, Fujian Province, China – sequence: 3 givenname: Qing-Mei surname: Zheng fullname: Zheng, Qing-Mei organization: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China – sequence: 4 givenname: Ya-Duan surname: Wang fullname: Wang, Ya-Duan organization: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China – sequence: 5 givenname: Qiu-Kai surname: Huang fullname: Huang, Qiu-Kai organization: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China – sequence: 6 givenname: Xuan surname: Song fullname: Song, Xuan organization: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China – sequence: 7 givenname: He surname: Wang fullname: Wang, He organization: School of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, Fujian Province, China – sequence: 8 givenname: Nan-Wen surname: Zhang fullname: Zhang, Nan-Wen organization: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China – sequence: 9 givenname: Yi-Hua surname: Zhu fullname: Zhu, Yi-Hua organization: Department of Ophthalmology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350122, Fujian Province, China – sequence: 10 givenname: Xiao-Le surname: Chen fullname: Chen, Xiao-Le organization: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China – sequence: 11 givenname: Ju-Hua surname: Yang fullname: Yang, Ju-Hua organization: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian Province, China |
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Snippet | To evaluate the feasibility of promoting genetic detection for granular corneal dystrophy type 2 (GCD
) by a questionnaire conducted among citizens in five... AIM: To evaluate the feasibility of promoting genetic detection for granular corneal dystrophy type 2 (GCD2) by a questionnaire conducted among citizens in... AIMTo evaluate the feasibility of promoting genetic detection for granular corneal dystrophy type 2 (GCD2) by a questionnaire conducted among citizens in five... |
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StartPage | 1976 |
SubjectTerms | corneal opacity excimer laser surgery granular corneal dystrophy type 2 Investigation |
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Title | A recognition survey of granular corneal dystrophy type 2 genetic detection in China |
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