Chemistry of Indoles : New Reactivities of Indole Nucleus and Its Synthetic Application

• Published in: YAKUGAKU ZASSHI Vol. 119; no. 1; pp. 35 - 60
• Main Author: MURAKAMI, Yasuoki
• Format: Journal Article
• Language: Japanese
• Published: Japan The Pharmaceutical Society of Japan 01.01.1999
• Subjects: bromination; Chemistry, Organic; debenzylation; debromination; Fischer indole synthesis; Friedel-Crafts reaction; Indoles - chemical synthesis; Indoles - chemistry; Organic Chemistry Phenomena; Vilsmeier-Haack reaction

This review summarizes our studies on the development of new reactivities of the indole nucleus and on its application for the synthesis. These studies involve the following five main subjects : 1) The Vilsmeier-Haack reaction was applied to 1, 2, 3, 4-tetrahydrocarbazole and its N-alkyl compounds....