The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

► IL-4 down-regulates mRNA levels of LPS-induced inflammatory cytokines and chemokines. ► IL-4 causes an early up-regulation of IL-10, RIPK2, RP105 and c-Maf mRNA. ► IL-4 suppresses LPS-induced TNFα production independently of IL-4-induced IL-10. ► The anti-inflammatory actions of IL-4 are independe...

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Bibliographic Details
Published inCytokine (Philadelphia, Pa.) Vol. 58; no. 3; pp. 415 - 423
Main Authors Woodward, Eleanor A., Kolesnik, Tatiana B., Nicholson, Sandra E., Prêle, Cecilia M., Hart, Prue H.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.06.2012
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