Anti-food and anti-microbial IgG subclass antibodies in inflammatory bowel disease

• Published in: Scandinavian journal of gastroenterology Vol. 51; no. 12; p. 1453
• Main Authors: Jansen, Anke, Mandić, Ana D, Bennek, Eveline, Frehn, Lisa, Verdier, Julien, Tebrügge, Irene, Lutz, Holger, Streetz, Konrad, Trautwein, Christian, Sellge, Gernot
• Format: Journal Article
• Language: English
• Published: England 01.12.2016
• Subjects: Adult; Aged; Animals; Antibodies, Bacterial - blood; Antibodies, Fungal - blood; Bacteroides fragilis; Biomarkers - blood; Case-Control Studies; Escherichia coli; Female; Food Hypersensitivity - blood; Germany; Humans; Immunoglobulin A - blood; Immunoglobulin G - blood; Inflammatory Bowel Diseases - blood; Inflammatory Bowel Diseases - immunology; Male; Microbiota; Middle Aged; Milk - adverse effects; ROC Curve; Saccharomyces cerevisiae; Triticum - adverse effects; Young Adult; microbiota; Food intolerance; biomarkers; inflammatory bowel disease; IgG subclasses

Inflammatory bowel disease (IBD), particularly Crohn's disease (CD), is associated with increased microbial-specific IgG and IgA antibodies, whereas alterations of anti-food antibodies are still disputed. The knowledge about IgG subclass antibodies in IBD is limited. In this study we analysed I...