Inhibition of TRPM8 Channels Reduces Pain in the Cold Pressor Test in Humans - Winchester, Wendy J.; Gore, Katrina; Glatt, Sophie; Petit, Wendy; Gardiner, Jennifer C.; Conlon, Kelly; Postlethwaite, Michael; Saintot, Pierre-Philippe; Roberts, Sonia; Gosset, James R.; Matsuura, Tomomi; Andrews, Mark D.; et al. (The Journal of pharmacology and experimental therapeutics, 2014)
Keywords: Animals; Body Temperature - drug effects; Cold Temperature; Cross-Over Studies; Double-Blind Method; Guinea Pigs; HEK293 Cells; Humans; Male; Membrane Transport Modulators - pharmacology; Oxycodone - pharmacology; Pain - drug therapy; Pain - metabolism; Rats; Rats, Wistar; TRPM Cation Channels - antagonists & inhibitors; TRPM Cation Channels - metabolism; WS-12; UGT; AE; TRPA1; CI; VAS; TRPV1; AUCcpt0-120; AUC; PF-05105679; ECS; HEK-293; HBSS; TRPM8; FDSS; CID