Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment - Poznanski, Sophie M.; Singh, Kanwaldeep; Ritchie, Tyrah M.; Aguiar, Jennifer A.; Fan, Isabella Y.; Portillo, Ana L.; Rojas, Eduardo A.; Vahedi, Fatemeh; El-Sayes, Abdullah; Xing, Sansi; Butcher, Martin; Lu, Yu; et al. (Cell metabolism, 2021)
Keywords: Adult; Aged; Animals; Antineoplastic Agents - immunology; Cell Line, Tumor; Female; Humans; Immunotherapy - methods; Killer Cells, Natural - cytology; Killer Cells, Natural - immunology; Male; Mice; Middle Aged; Neoplasms - therapy; Tumor Microenvironment; Young Adult; NK cells; metabolic flexibility; immunometabolism; cancer immunotherapy; NK cell metabolism; tumor microenvironment; adoptive cell therapy; glucose metabolism; oxidative stress; Warburg effect