Indole Compound NC009-1 Augments APOE and TRKA in Alzheimer's Disease Cell and Mouse Models for Neuroprotection and Cognitive Improvement - Chen, Yi-Chun; Chiu, Ya-Jen; Lin, Chih-Hsin; Hsu, Wen-Chuin; Wu, Jia-Lu; Huang, Chen-Hsiang; Lin, Chia-Wei; Yao, Ching-Fa; Huang, Hei-Jen; Lo, Yen-Shi; Chen, Chiung-Mei; Wu, Yih-Ru; et al. (Journal of Alzheimer's disease, 2019)
Keywords: Aged; Aged, 80 and over; Alzheimer Disease - drug therapy; Alzheimer Disease - genetics; Alzheimer Disease - psychology; Animals; Apolipoproteins E - metabolism; Behavior, Animal; Biomarkers - analysis; Cell Line; Cognition - drug effects; Female; Gene Expression - drug effects; Humans; Indoles - pharmacology; Male; Mice; Mice, Transgenic; Neurites - drug effects; Neurons - drug effects; Neuroprotection - drug effects; Neuroprotective Agents - pharmacology; Receptor, trkA - metabolism; amyloid-β; indole compound; TRKA; APOE; Alzheimer’s disease; biomarker