Clock-Talk: Interactions between Central and Peripheral Circadian Oscillators in Mammals

• Published in: Cold Spring Harbor Symposia on Quantitative Biology Vol. 80; p. 223
• Main Authors: Schibler, Ueli, Gotic, Ivana, Saini, Camille, Gos, Pascal, Curie, Thomas, Emmenegger, Yann, Sinturel, Flore, Gosselin, Pauline, Gerber, Alan, Fleury-Olela, Fabienne, Rando, Gianpaolo, Demarque, Maud, Franken, Paul
• Format: Journal Article
• Language: English
• Published: United States 01.01.2015
• Subjects: Actins - metabolism; Animals; Biological Clocks; Body Temperature - physiology; Circadian Clocks - physiology; Circadian Rhythm - physiology; Cues; Fasting - physiology; Feeding Behavior - physiology; Glucocorticoids - metabolism; Humans; Mammals; Mice; Rats; Receptors, Glucocorticoid - metabolism; Retina - physiology; Signal Transduction; Suprachiasmatic Nucleus - physiology
• ISSN: 1943-4456
• DOI: 10.1101/sqb.2015.80.027490

In mammals, including humans, nearly all physiological processes are subject to daily oscillations that are governed by a circadian timing system with a complex hierarchical structure. The central pacemaker, residing in the suprachiasmatic nucleus (SCN) of the ventral hypothalamus, is synchronized d...