Effects of Moxifloxacin on Human Neutrophil and T-Lymphocyte Functions in Vitro

• Published in: Pharmaceuticals (Basel, Switzerland) Vol. 3; no. 12; pp. 3570 - 3580
• Main Authors: Potjo, Moliehi, Cockeran, Riana, Theron, Annette J, Feldman, Charles, Anderson, Ronald
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.12.2010; MDPI
• Subjects: calcium; CD25; elastase; interleukin-2; mitogen-activated proliferation; N-formyl-L-methionyl-L-leucyl-L-phenylalanine; phorbol myristate acetate; reactive oxygen species

Moxifloxacin is useful in the treatment of respiratory infections, including community-acquired pneumonia, and also shows promise in the treatment of tuberculosis, a clinical setting which necessitates extended administration of this agent. Relatively little is known, however, about the effects of t...