Overview of Nomenclature of Nuclear Receptors

• Published in: Pharmacological reviews Vol. 58; no. 4; pp. 685 - 704
• Main Authors: Germain, Pierre, Staels, Bart, Dacquet, Catherine, Spedding, Michael, Laudet, Vincent
• Format: Journal Article
• Language: English
• Published: United States American Society for Pharmacology and Experimental Therapeutics 01.12.2006
• Subjects: Animals; Binding Sites; Binding Sites - genetics; Biochemistry, Molecular Biology; Gene Expression Regulation; Humans; Life Sciences; Ligands; Molecular biology; Receptors, Cytoplasmic and Nuclear; Receptors, Cytoplasmic and Nuclear - classification; Receptors, Cytoplasmic and Nuclear - genetics; Receptors, Cytoplasmic and Nuclear - physiology; Terminology; Terminology as Topic

Nuclear receptor pharmacology has, to a certain extent, led the way, compared with other receptor systems, in the appreciation that ligands may exert very diverse pharmacology, based on their individual chemical structure and the allosteric changes induced in the receptor/accessory protein complex....