Exploring non-coding RNA mechanisms in hepatocellular carcinoma: implications for therapy and prognosis

• Published in: Frontiers in immunology Vol. 15; p. 1400744
• Main Authors: Tian, Yu, Zhang, Meng, Liu, Li-xia, Wang, Zi-chao, Liu, Bin, Huang, Youcai, Wang, Xiaoling, Ling, Yun-zhi, Wang, Furong, Feng, Xiaoqiang, Tu, Yanyang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 2024
• Subjects: Animals; Biomarkers, Tumor - genetics; Carcinoma, Hepatocellular - diagnosis; Carcinoma, Hepatocellular - genetics; Carcinoma, Hepatocellular - therapy; diagnosis and prognosis; epigenetic factors; Gene Expression Regulation, Neoplastic; hepatocellular carcinoma; Humans; Liver Neoplasms - diagnosis; Liver Neoplasms - genetics; Liver Neoplasms - therapy; MicroRNAs - genetics; miRNA sponge; Prognosis; RNA, Long Noncoding - genetics; RNA, Untranslated - genetics; therapy resistance; miRNA sponge; epigenetic factors; hepatocellular carcinoma; diagnosis and prognosis; therapy resistance
• ISSN: 1664-3224; 1664-3224
• DOI: 10.3389/fimmu.2024.1400744

Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related deaths in the world. The development and progression of HCC are closely correlated with the abnormal regulation of non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (ci...