Plasma levels of increased miR-195-5p correlates with the sFLT-1 levels in preeclampsia

• Published in: Hypertension in pregnancy Vol. 35; no. 2; pp. 150 - 158
• Main Authors: Sandrim, Valeria Cristina, Eleuterio, Nibia, Pilan, Eliane, Tanus-Santos, Jose Eduardo, Fernandes, Karla, Cavalli, Ricardo
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 02.04.2016
• Subjects: Adult; Circulating microRNA; Female; Humans; microRNA; MicroRNAs - blood; miR-195; PCR-array; Pre-Eclampsia - blood; preeclampsia; Pregnancy; sFLT-1; Vascular Endothelial Growth Factor Receptor-1 - blood; Young Adult; microRNA; miR-195; preeclampsia; sFLT-1; Circulating microRNA; PCR-array
• ISSN: 1064-1955; 1525-6065; 1525-6065
• DOI: 10.3109/10641955.2015.1122034

Although the role of soluble fms-like tyrosine kinase 1 (sFLT-1) in preeclampsia is well-established, the mechanism related to its synthesis remains poorly understood. We evaluated the association among the circulating microRNAs (miRs) and sFLT-1 levels in preeclampsia pregnant women. For this purpo...