Real-time imaging of human cortical activity evoked by painful esophageal stimulation

• Published in: Gastroenterology (New York, N.Y. 1943) Vol. 128; no. 3; p. 610
• Main Authors: Hobson, Anthony R, Furlong, Paul L, Worthen, Sian F, Hillebrand, Arjan, Barnes, Gareth R, Singh, Krish D, Aziz, Qasim
• Format: Journal Article
• Language: English
• Published: United States 01.03.2005
• Subjects: Adult; Brain Mapping; Cerebral Cortex - physiopathology; Computer Systems; Dominance, Cerebral; Electric Stimulation; Esophagus - physiopathology; Evoked Potentials, Somatosensory; Female; Gyrus Cinguli - physiopathology; Humans; Magnetoencephalography; Male; Pain - etiology; Pain - physiopathology; Pain Measurement; Somatosensory Cortex - physiopathology

Current models of visceral pain processing derived from metabolic brain imaging techniques fail to differentiate between exogenous (stimulus-dependent) and endogenous (non-stimulus-specific) neural activity. The aim of this study was to determine the spatiotemporal correlates of exogenous neural act...