Efficacy of Cefepime in the Treatment of Infections Due to Multiply Resistant Enterobacter Species

• Published in: Clinical infectious diseases Vol. 23; no. 3; pp. 454 - 461
• Main Authors: Sanders, W. Eugene, Tenney, James H., Kessler, Robert E.
• Format: Journal Article
• Language: English
• Published: Chicago, IL University of Chicago Press 01.09.1996
• Subjects: Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antimicrobials; Bacteremia; beta-Lactam Resistance; Biological and medical sciences; Blood; Cefepime; Cephalosporins; Cephalosporins - therapeutic use; Clinical Articles; Enterobacter; Enterobacter - drug effects; Enterobacter - isolation & purification; Enterobacteriaceae Infections - diagnosis; Enterobacteriaceae Infections - drug therapy; Europe; Humans; Infections; Medical sciences; Microbial Sensitivity Tests; Pharmacology. Drug treatments; Sputum; Symptoms; United States; Urinary tract infections; Urine; Infection; Human; Antibiotic; Chemotherapy; Enterobacter; Treatment; Intravenous administration; Treatment efficiency; Bacteriosis; Bacteria; Enterobacteriaceae

Cefepime is a new cephalosporin with an enhanced antibacterial potency and spectrum. More rapid penetration into many gram-negative bacilli, targeting of multiple penicillin-binding proteins, and resistance to inactivation by many β-lactamases account for its activity against organisms that have dev...