FLUXestimator: a webserver for predicting metabolic flux and variations using transcriptomics data

• Published in: Nucleic acids research Vol. 51; no. W1; pp. W180 - W190
• Main Authors: Zhang, Zixuan, Zhu, Haiqi, Dang, Pengtao, Wang, Jia, Chang, Wennan, Wang, Xiao, Alghamdi, Norah, Lu, Alex, Zang, Yong, Wu, Wenzhuo, Wang, Yijie, Zhang, Yu, Cao, Sha, Zhang, Chi
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 05.07.2023
• Subjects: Animals; Humans; Metabolic Networks and Pathways; Metabolomics; Mice; Models, Biological; Software; Transcriptome; Web Server Issue

Abstract Quantitative assessment of single cell fluxome is critical for understanding the metabolic heterogeneity in diseases. Unfortunately, laboratory-based single cell fluxomics is currently impractical, and the current computational tools for flux estimation are not designed for single cell-leve...