Real-world analysis of treatment patterns and clinical outcomes in patients with newly diagnosed chronic lymphocytic leukemia from seven Latin American countries

• Published in: Hematology (Luxembourg) Vol. 25; no. 1; pp. 366 - 371
• Main Authors: Chiattone, Carlos, Gomez-Almaguer, David, Pavlovsky, Carolina, Tuna-Aguilar, Elena J., Basquiera, Ana L., Palmer, Luis, de Farias, Danielle Leao Cordeiro, da Silva Araujo, Sergio Schusterschitz, Galvez-Cardenas, Kenny Mauricio, Gomez Diaz, Alvaro, Lin, Jennifer H., Chen, Yen-wen, Machnicki, Gerardo, Mahler, Michelle, Parisi, Lori, Barreyro, Paula
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.01.2020
• Subjects: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols - administration & dosage; Antineoplastic Combined Chemotherapy Protocols - adverse effects; chlorambucil; chronic lymphocytic leukemia; Disease-Free Survival; Female; fludarabine; Humans; Latin America; Latin America - epidemiology; Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis; Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy; Leukemia, Lymphocytic, Chronic, B-Cell - mortality; Male; Middle Aged; overall survival; progression-free survival; real-world evidence; Risk Factors; Survival Rate; treatment pattern; Latin America; chronic lymphocytic leukemia; real-world evidence; progression-free survival; fludarabine; overall survival; chlorambucil; treatment pattern; Latin America

To describe chronic lymphocytic leukemia (CLL) treatment patterns and patient outcomes in Latin America. This chart review study (NCT02559583; 2008-2015)evaluated time to progression (TTP) and overall survival (OS) outcomes among patients with CLL who initiate done (n = 261) to two (n = 96) lines of...